Cerebral cavernous malformations and movement disorders
Objective: To present the unusual occurrence of movement disorders (MD) secondary to cerebral cavernous malformations (CCM). Background: CCM most frequently become manifest by seizures, focal…Opposing effects of levodopa on basal ganglia activity in Parkinson’s disease during motion and rest
Objective: To explore the pattern of activation within the motor network during the movement and resting phases of the tapping task in Parkinson’s disease (PD)…Impulse control disorders and (romantic) jealousy in Parkinson’s disease: a patients’ vs. partners’ perspective
Objective: To compare self-reported symptoms of (romantic) jealousy and impulse control disorders (ICD) in Parkinson’s disease (PD) patients to those reported by their partners. Background:…Clinical and DAT Imaging Characteristics of Participants with Scans without Evidence of Dopaminergic Deficit (SWEDDs): PPMI Cohort 2 year follow-up
Objective: To examine the clinical and biological characteristics of participants with scans without evidence of dopaminergic deficit (SWEDD) during a two-year follow-up. Background: Study participants…Subthalamic Neurons Fire Differently In Planned Versus Reactive Movements
Objective: To study the role of STN neurons in modifying an ongoing movement. Background: Patients with Parkinson’s Disease (PD) have difficulty starting or modifying a…Dopaminergic imaging in patients with basal ganglia calcification presenting with parkinsonism
Objective: To evaluate the integrity of the nigro-striatal system with single photon emission computed tomography imaging with dopamine transporter (DaTscan) in patients with basal ganglia…Substantia Nigra (SN) Hyperechogenicity as seen in Transcranial Sonography (TCS) is a reliable disease progression marker from Stage I to Stage II in Early Onset Parkinson’s Disease (EOPD)
Objective: To test the hypothesis that SN hyperechogenicity seen in transcranial sonography (TCS) can be used as a reliable disease progression marker from stage I…Spatial distribution of functional clusters coding for reward and movement information in the striatal direct and indirect pathways
Objective: To obtain the insight how striatum processes reward based learning and motor information, we explored the responses of D1 and D2 medium spiny neurons…Oscillaotory activity in the globus pallidus internus in patients with Parkinson’s disease
Objective: To quantify the characteristics of oscillatory neurons in the GPi in patients with PD. Background: Abnormal oscillatory activity has been predicted to play a…Striatal dopaminergic dysregulation and dystonia-like movements induced by peripheral nerve crush in a transgene DYT1 mouse model
Objective: To study changes of the dopaminergic pathway of a transgene DYT1 dystonia mouse model after induction of a dystonic phenotype by peripheral nerve crush.…
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