Subthalamic nucleus activity during virtual reality provoked lower limb freezing in a patient with Parkinson’s disease and freezing of gait
Objective: Record subthalamic nucleus activity in a Parkinson's disease patient with gait freezing while they perform a virtual reality walking task during DBS surgery. Background:…Apraxia in Parkinson’s disease
Objective: We aim to study apraxia in Parkinson's disease. Background: Limb apraxia is a cognitive motor disorder of skilled, purposive movements not caused by elementary…The small GTP-binding protein Rhes influences midbrain dopaminergic neurons: Behavioral and biochemical studies
Objective: Rhes is a small GTP-binding protein highly enriched in the striatum, developmentally regulated by thyroid hormone, and by dopamine (DA) innervation in adult rat…Attention to action: Common to both conversion (psychogenic) and Parkinsonian (neurogenic) motor speech disorders
Objective: To review and present a common abnormality --- attention to action--- underlying Parkinsonian and conversion speech disorders. Background: Conversion speech disorders are characterized by…A case of thalamic malignant glioma formation in a patient with STN-DBS for Parkinson’s disease
Objective: We present a case of development of malignant glioma (glioblastoma multiforme) in the area adjacent to electrostimulation zone in a patient with chronic STN-DBS,…Long term recordings of subthalamic ocillatory activity in patients with Parkinson’s disease
Objective: The aim of this study was to investigate the stability of beta oscillations (13 - 30 Hz) in the subthalamic nucleus (STN) of patients…In-vivo free-water imaging and functional connectivity in a knock-in mouse model of DYT1 dystonia
Objective: To examine in-vivo functional connectivity and free-water diffusion imaging in dystonic mutant Tor1a knock-in (DYT1) and wild-type (WT) control mice. We test the hypothesis…Comparative study of the substantia nigra echogenicity and 123-I ioflupane SPECT in patients with REM behavior disorder
Objective: To compare (1) the echogenicity of substantia nigra (SN) in subjects with idiopathic REM behavior disorder (iRBD) and healthy controls and (2) to determine…Striatal PDE10 expression in Parkinson’s disease (PD) and healthy controls using [18F]MNI-659 PET imaging
Objective: To evaluate the feasibility of [18F]MNI-659 PET, a striatal PDE10A imaging tracer, as a imaging biomarker in PD. Background: PDE10 is highly and specifically…Pallidal low frequency activity correlates with dystonic symptoms in patients with cervical dystonia
Objective: The aim of this study was to investigate the potential association between pallidal 4–12 Hz activity and symptom severity as quantified by the Toronto…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.