LRRK2 Mutation in a Patient with NMDA and GAD 65 Antibodies
Objective: To describe case of a patient who presented with a history of autoimmune encephalitis with NMDA receptor and GAD 65 antibodies positive in cerebrospinal…Neuropsychiatric profile of progressive supranuclear palsy phenotypes
Objective: To analyze neuropsychiatric symptoms among phenotypes of patients with Progressive supranuclear palsy (PSP) in movement disorder centers in Colombia and Mexico. Background: Progressive supranuclear…Noradrenaline treatment of apathy and impulsivity in participants with Progressive Supranuclear Palsy syndromes (NORAPS)
Objective: The NORAPS phase II study (ISRCTN99462035) investigates the safety, tolerability and efficacy of atomoxetine in Progressive Supranuclear Palsy (PSP). Background: PSP is a neurodegenerative…The Feedback Loop: Illness Perceptions and Motor Complications in Parkinson’s
Objective: To explore the relationship between motor complications, illness perceptions and cognitive beliefs about symptoms in people with Parkinson's disease (PwP). Background: Around 50% PwP…Cognitive and Neuropsychiatric Dysfunction is Associated with Corticostriatal Synucleinopathy in the Alpha-Synuclein Preformed Fibril Rat Model of Parkinson’s Disease
Objective: To investigate the role of corticostriatal synucleinopathy on behavioral function in an alpha-synuclein preformed fibril (a-Syn PFF) rat model of Parkinson’s disease (PD). Background:…Exploring Visual Scanning Behavior and Novelty Seeking in Parkinson’s Disease: A Pilot Study
Objective: To assess the feasibility of eye-tracking metrics in a Visual Paired Comparison (VPC) task as biomarkers for impulsivity in Parkinson's disease (PD) and to…VPS13C: a Modifier Gene causing Suboptimal Response to Levodopa in Early-Onset Parkinson’s Disease
Objective: To describe a retrospective clinical study of four cases carrying heterozygous pathogenic variants in the VPS13C gene with a clinical diagnosis of Early-Onset Parkinson’s…Clinical and Epidemiological Aspects of Neuropsychiatric Features in Patients with Huntington Disease in Chile
Objective: To describe the prevalence of motor and neuropsychiatric symptoms in HD patients seen at the Center of Movement Disorders (CETRAM), Santiago, Chile. Background: There…Clinico- radiological profile of four patients with CSF1R- related leukoencephalopathy: A case series from India
Objective: We aimed to describe the clinical, radiological and genetic profile of patients with CSF1R- related leukoencephalopathy. Background: CSF1R- related leukoencephalopathy is a rare dominantly…The Neuroprotective Effects of Rolipram, a Selective Phosphodiesterase IV Inhibitor, on Parkinson’s Disease in Rat Models: A Pharmacological Exploration in both In vivo and In vitro Settings
Objective: Our research sought to unravel the pharmacological effects and mechanisms of action of Rolipram through both in vivo and in vitro experimentation in models…
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