Antidepressants in Huntington’s Disease: A Meta Analysis of Mood and Motor Outcomes with Placebo-controlled Trials
Objective: To evaluate the efficacy of antidepressants for depression in Huntington’s disease (HD). Background: Depression is highly prevalent in HD. Despite frequent clinical use of…Depressive Symptoms and Functional Impairment in Huntington’s Disease A Brazilian Cohort Study
Objective: To investigate the prevalence of psychiatric manifestations in Huntington’s disease (HD) and examine their association with functional disease stages. Background: HD is an autosomal…Efficacy and Adverse Events of Tetrabenazine, Deutetrabenazine, and Valbenazine in Huntington’s Disease
Objective: To compare the efficacy and safety of tetrabenazine, deutetrabenazine, and valbenazine for chorea and neuropsychiatric outcomes in Huntington’s disease (HD). Background: Vesicular monoamine transporter…Psychiatric Symptoms and Quality of Life in Huntington’s Disease Evidence from a Brazilian Cohort
Objective: To investigate the association between psychiatric manifestations and perceived quality of life in patients with Huntington’s disease (HD). Background: HD is a progressive neurodegenerative…Anti-IgLON5 Encephalitis Presenting as Chronic Progressive Asymmetrical Ataxia and Chorea
Objective: To report a case of gait instability and progressive asymmetrical chorea clinically confirmed as anti-IgLON5 encephalitis. Background: Anti-IgLON5 encephalitis is a rare autoimmune neurological…A biomarker of Huntington’s disease progression derived from deep neural speech representations
Objective: To derive a speech-based score reflecting Huntington’s disease (HD) progression from deep neural representations of raw voice recordings and evaluate its potential as a…Sleep Architecture and Cognitive Performance in Early Huntington’s Disease: A Pilot Study
Objective: Characterize sleep architecture and cognitive performance in people with early Huntington’s disease (HD) and explore their associations. Background: Cognitive impairment is a devastating feature…Sleep Disturbances in Huntington’s Disease A Cross-Sectional Study
Objective: To determine the prevalence of poor sleep quality in HD mutation carriers and to characterize objective sleep parameters. Background: HD is a progressive neurodegenerative…Speech Changes as Biomarkers in Huntington’s Disease: a Meta-Analysis
Objective: To perform a meta-analysis evaluating acoustic speech features as potential biomarkers of Huntington’s disease by comparing individuals with manifest HD and premanifest HD to…Non-motor symptoms in Huntington’s disease: Results from the Validation of the Non-motor Symptoms Scale (MDS-NMS)
Objective: To present validation results of the Movement Disorder Society Non-Motor Symptoms Scale (MDS-NMS), originally developed for Parkinson’s disease, for use in people with Huntington’s…
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