Effectiveness and Safety of Deutetrabenazine in Chinese Patients with Huntington’s Disease-associated Chorea: A Multicenter Phase 4 Study
Objective: To evaluate the effectiveness and safety of deutetrabenazine (DTBZ) in Chinese patients with Huntington’s Disease (HD)-associated chorea. Background: Chorea is a key symptom of…Perception of Early-Intervention Therapies and Clinically Meaningful Delays in Huntington’s Disease Onset and Progression: The Pre-HDBOI Study
Objective: To characterize willingness among people with premanifest Huntington’s disease (PwPHD) to consider early-intervention therapies if available, the minimally acceptable delay in HD onset/progression, and…A mindfulness-based intervention course in pre-manifest Huntington’s disease: analysis of pilot data
Objective: To assess feasibility and initial outcomes of a mindfulness-based intervention course in patients with pre-manifest, genetically confirmed Huntington’s disease (HD). Background: Mindfulness-based intervention courses…Patient Experience and Satisfaction With Once-Daily Deutetrabenazine Extended-Release Tablets for Treatment of Huntington Disease-Related Chorea
Objective: Objectives of this study were to explore patient-reported ease of use, effectiveness, and satisfaction during real-world use of once-daily (QD) deutetrabenazine extended-release tablets in…Valbenazine Improves Chorea Across Multiple Body Regions in Adults With Huntington’s Disease
Objective: To evaluate valbenazine’s effects on chorea across body regions in adults with Huntington’s disease (HD) using data from KINECT®-HD (NCT04102579). Background: Once-daily valbenazine is…Decreased Disease Burden in Motor-Related HD-HI Domains Among Adults With Huntington’s Disease Treated With Valbenazine
Objective: To evaluate the effects of valbenazine (VBZ) on mobility, abnormal movements, and hand/arm function as assessed using the Huntington’s Disease Health Index (HD-HI). Background:…Long-Term Safety and Efficacy of Valbenazine for Treating Huntington’s Disease Chorea
Objective: To present safety and efficacy results from a long-term study of once-daily valbenazine for chorea associated with Huntington’s disease (HD). Background: In a 12-week…Long-term results of pallidal deep brain stimulation in patients with Huntington’s disease
Objective: To analyze long-term results of pallidal (GPi) deep brain stimulation (DBS) in patients with Huntington's disease (HD). Background: In HD, DBS is suggested to…Analysis of Emergency Department Encounters and Hospital Admissions of People with Huntington’s Disease
Objective: Define characteristics of emergency department encounters and hospital admissions of people with Huntington’s disease and identify opportunities for intervention to reduce hospitalizations. Background: Huntington’s…Efficacy and Safety of Deutetrabenazine in Huntington’s Disease: a Systematic Review
Objective: To evaluate efficacy and safety of deutetrabenazine (DTB) in Huntington's Disease (HD) in order to guide evidence-based clinical decisions. Background: HD is a genetic…
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