Modifying clinical and electrophysiological parameters through Transcranial pulsed current stimulation (tPCS) in Huntington disease
Objective: 1. To assess brain network dysfunction of Huntington disease (HD). 2. To evaluate the effectiveness of 2-week home-based chronic non-invasive transcranial brain stimulation to…Hazard ratios of suicidality in a large Huntington disease population compared with controls: marginal structural modeling of Enroll-HD registry data
Objective: The aim of this study was to describe the risk of suicidality among individuals with versus those without Huntington disease (HD) from Enroll-HD. Background:…Effects of a small molecule angiotensin IV analog on Huntington’s disease animal model
Objective: The present study was designed to test if N-hexanoic-Tyr-Ile-(6)-amino hexanoic amide (AngIV-6a), an angiotensin IV analog, could attenuate 3-nitropropionic acid-induced Huntington’s disease-like symptoms in…Telemedicine and in-person encounters in a Huntington’s disease cohort: virtually the same
Objective: The aim of this study was to assess the impact of virtual care provision modalities (VPM) on patient satisfaction (PS) metrics for the specialized…Emerging treatments targeting DNA and RNA in Huntington’s disease: a review of future perspectives and current challenges
Objective: To review the progress made towards the development of a huntingtin (HTT) lowering strategy based on RNA and DNA and also to assess the…A case of trichotillomania as the preceding symptom of Huntington’ s diseaseand the effect of risperidone
Objective: Huntington's disease (HD) is a rare neurodegenerative disorder inherited by an autosomal dominant fashion which is most commonly characterised by choreic movement disorders. However,…Real-world effectiveness and safety of deutetrabenazine in patients with chorea associated with Huntington disease
Objective: To assess real-world effectiveness and safety of deutetrabenazine (DTBZ) for chorea associated with Huntington disease (HD). Background: Real-world evidence on the impact of DTBZ…Treatment of chorea in pediatric subjects with pallidal and thalamic deep brain stimulation
Objective: Assess the utility of deep brain stimulation (DBS) in treatment of chorea in pediatric patients. Background: While DBS has become common in treatment of…AAV5-miHTT gene therapy mediates sustained mutant huntingtin lowering in brain and cerebrospinal fluid of Huntington’s disease minipigs up to 5 years
Objective: Our objective is to assess long-term safety of and durability of an adeno-associated viral vector serotype 5 encoding an engineered miRNA (AAV5-miHTT) targeting human…Neurologic music therapy for fine motor rehabilitation in Huntington’s disease: a pilot study
Objective: To present preliminary evidence of fine motor rehabilitation in patients with Huntington’s disease using neurologic music therapy. Background: Huntington’s disease (HD) is an autosomal…
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