Effect of Subthalamic Deep Brain Stimulation (DBS) on Impulsive Control Disorders (ICD) and Dopamine Dysregulation Syndrome (DDS) – A Randomized Controlled Trial Evaluating Deep Brain Stimulation Using a New Multiple Source, Constant-Current Rechargeable System for Management of Symptoms of Parkinson’s Disease (INTREPID)
Objective: To evaluate impulse control in participating subjects of the INTREPID randomized controlled trial (RCT). Background: Parkinson’s disease (PD) patients undergoing treatment with either medications…Dynamics of Device-based Treatments for Parkinson´s Disease in Germany from 2010 – 2017
Objective: Analyze the patient profiles and dynamics of utilization of Continuous Subcutaneous Apomorphine Infusion (CSAI), Levodopa-carbidopa Intestinal Gel (LCIG), and Deep Brain Stimulation (DBS) for…Changes in close relationships among patients with Parkinson’s disease and their partners following initiation of device-aided treatment
Objective: Our primary objective was to study whether there is a difference in how close relationships are perceived by Parkinson’s disease (PD) patients with device-aided…Patient-Centered Outcomes of Deep Brain Stimulation in Parkinson’s Disease
Objective: To evaluate patient-centered outcomes after deep brain stimulation in Parkinson's disease. Background: Deep brain stimulation (DBS) is an effective treatment for Parkinson's disease (PD) patients. Long-term…Directional lead local field potentials show distinct spatial resolution
Objective: To characterize the spatio-spectral patterns of local field potentials (LFPs) in the subthalamic nucleus (STN) recorded from segmented DBS electrodes. Background: PD patients in…Two Patients with Dopamine Transporter Deficiency Treated with Deep Brain Stimulation
Objective: Dopamine transporter deficiency syndrome (DTDS,) a rare disease characterized by infantile –onset progressive dystonia, has no established treatment guidelines. Treatment is generally predicated on…Subthalamic Nucleus of Luys: A review. What has evolved since 1865?
Objective: The review provides detailed material about the Subthalamic Nucleus of Luys, including pathophisiolgy, hystorical notes about Luys, embryology, anatomy, principal afferents and efferents pathways, as…Interleaved deep brain stimulation for dyskinesia management in Parkinson’s disease
Objective: To evaluate the clinical effects of using interleaving stimulation to simultaneously treat Parkinson’s disease (PD) symptoms and dyskinesia by the generation of two symptom-specific…Intraoperative test stimulation of the subthalamic nucleus reduces the search space for chronic stimulation settings in Parkinson’s disease
Objective: To determine whether intraoperative test stimulation is indicative of postoperative stimulation results. Background: It is unknown whether intraoperative testing during awake Deep Brain Stimulation…Correlation of local field potentials (LFPs) to electromyography (EMG) of the rostral zona incerta (rZI) and subthalamic nucleus (STN) in Parkinson’s Disease (PD)
Objective: To provide a proof of concept of correlating LFPs to EMG during multi tasks in PD subtypes. Background: Evidence highlights the unique contributions of…
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