Baseline plasma neurofilament light and phosphorylated tau 181 levels predict longitudinal cognitive decline in APOE4 and long SNCA Rep1 carriers in Parkinson’s disease
Objective: Plasma neurofilament light (NfL; a marker of axonal injury) and phosphorylated tau 181 (pTau181) are biomarkers that have been associated with cognitive decline in…Normative Data for the IDEA Dementia Screen in Healthy Older Adults and People with Parkinson’s Disease in Ethiopia: A Comparative Cross Sectional Study
Objective: This study aims to establish Ethiopian normative data for IDEA in healthy older adults and People with Parkinson's disease, and to evaluate its appropriateness…Longitudinal cognitive trajectories and predictors of dementia conversion in Parkinson’s disease
Objective: To determine clinical predictors of longitudinal cognitive decline and dementia conversion in a real-world Parkinson’s disease (PD) cohort. Background: Cognitive impairment is one of…Cognition and Dementia in a Kenyan Parkinson’s Disease Cohort: A Sub-study of the TraPCAf Consortium
Objective: To describe Cognitive Impairment in the Kenyan PD TraPCAf cohort. Background: The epidemiology and natural history, including cognitive impairment (CI) of Parkinson's disease (PD)…Role of ApoE in α-Synuclein Pathology
Objective: To investigate whether apolipoprotein E (ApoE) isoforms directly interact with α-synuclein and determine how these interactions influence aggregation dynamics and cellular uptake. Background: The…A Switching from Oral Donepezil to a Twice-Weekly Korean Transdermal Donepezil Patch in Patients with Dementia with PD
Objective: Aimed to assess caregivers’ satisfaction with and preference for a transdermal donepezil patch compared with conventional oral formulations in patients with d-PD, with the…The Clinical and Neuropathological Factors Associated with Brain Atrophy in CSF1R-RD.
Objective: To characterize the clinical and neuropathological factors associated with brain atrophy in CSF1R-related disorder (CSF1R-RD). Background: CSF1R-RD is a rare, fatal autosomal dominant leukoencephalopathy…Raman Spectroscopic Identification of Biochemical Alterations in Post Mortem Brain Tissue Microarrays from Parkinsons and Alzheimers Disease
Objective: To investigate biochemical differences in neuronal, vascular and neuropil regions of post mortem brain tissue from Parkinsons disease and Alzheimers disease using Raman microscopy.…Predicting Dementia in Parkinson’s Disease Using Blood-Based Proteomics
Objective: To identify a proteomic profile associated with the future development of dementia in recently diagnosed Parkinson’s disease (PD) patients. Background: Dementia is a common…Strategies for Harmonising Clinical Data for Multi-Centre, Large Scale Genome-Wide Association Studies
Objective: To establish a data harmonisation framework for classifying cognitive status in Parkinson’s disease (PD) across multiple study and data types to facilitate large-scale genetic…
- « Previous Page
- 1
- 2
- 3
- 4
- 5
- …
- 39
- Next Page »