Feasibility of a simplified, symptom-based electronic diary to improve evaluation of motor and non-motor complications in Parkinson’s disease
Objective: To determine the feasibility of the simplified and symptom-based electronic PD diary and compare with the standard paper diary. Background: Motor complications (MC) is…Visuomotor reaction time can predict IQ in children
Objective: This study investigated whether visuomotor reaction time in 5 year-old children predicts intelligence test scores in 8 year-old children using the longitudinal approach. Background:…Home Based Care: A care pathway innovation for Parkinson’s disease
Objective: To create a new care pathway that puts the needs of the patient at the centre of service design and delivery. Background: The traditional…Burden of variants in Parkinson’s disease-associated genes in GBA mutation carriers
Objective: The main objective of this study is to examine the burden of variants in genes that are known or suspected to be involved in…Male-specific exacerbation of susceptibility to α-synuclein pre-formed fibrils by developmental dieldrin exposure in mice
Objective: To determine whether developmental exposure to dieldrin exacerbates susceptibility to α-synuclein (α-syn) preformed fibril (PFF)-induced synucleinopathy in adulthood. Background: Parkinson’s disease (PD) is characterized…Early life stress offers a window into the relationship between depression and Parkinson’s disease: A 60-week study after maternal separation in rats
Objective: The aim of this study was to examine the relationship between depression and Parkinson's disease (PD) using the rat model of maternal separation (MS).…The Personalized Parkinson Project – data quality enhancing strategies
Objective: Demonstrate the impact of quality enhancing strategies in the Personalized Parkinson Project. Background: Increasingly, the scientific community uses data from longitudinal observational patient cohorts…A Human Factors Study of the DopaFuse® Delivery System
Objective: SynAgile has developed the DopaFuse Delivery System to noninvasively and continuously administer oral LD/CD into the mouths of patients with PD. The System is…Increasing chances of detecting a neuroprotective signal in PhI/II PD clinical trials?
Objective: Design an early CT program to detect a neuroprotective signal in PD. Background: Attempts to develop PD modifying therapies have been largely disappointing so…5 cases Static Encephalopathy of childhood with NeuroDegeneration in Adulthood (OMIM 300894) in children
Objective: 5 russian female patients aged 3 to 6 years with different mutations of the WDR45 gene were examined. Background: To study the clinical picture…
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