Continuous circadian intracerebroventricular administration of anaerobic dopamine: A new therapeutic concept for Parkinson’s disease?
Objective: We aim to overcome these challenges by demonstrating that continuous i.c.v. of Anaerobic-dopamine (A-dopamine,Patent #WO2015173258 A1) close to the striatum is a feasible and…Sustained release triple drug loaded Microbaloons for management of Parkinson’s Disease
Objective: It is hypothesized that a drug delivery system that provides controlled and sustained release of PD drugs would afford better management of PD. Hollow…Appropriateness of DAT Scan Ordering in a University Hospital Practice
Objective: To examine the diagnostic utility (or misuse) of DAT scanning in a University Hospital practice – is there unnecessary utilisation of DAT scanning when…Quercetin Regulates Cadmium Induced Motor Dysfunction in Depletion of Dopamine and its Metabolites at Synapse
Objective: The present study has an attempt to understand cadmium induced alteration in dopamine and associated signaling that causes the motor alterations in rats and…Striatal dopaminergic dysregulation and dystonia-like movements induced by peripheral nerve crush in a transgene DYT1 mouse model
Objective: To study changes of the dopaminergic pathway of a transgene DYT1 dystonia mouse model after induction of a dystonic phenotype by peripheral nerve crush.…Neuropsychiatric manifestations in Parkinson’s disease
Objective: Evaluate the different neuropsychiatric manifestations in Parkinson's disease. Background: Parkinson's disease (PD) is the second most common neurodegenerative pathology after Alzheimer's disease, although PD…Cerebral differences between dopamine-resistant and dopamine-responsive Parkinson’s tremor
Objective: To disentangle the cerebral mechanisms underlying dopamine-resistant versus dopamine-responsive tremor in Parkinson’s disease. Background: Parkinson’s rest tremor is related to cerebral activity in both…Screening of mutations in PARK2 gene and Dopamine levels in Parkinson’s disease (PD) patients in Coimbatore population, India
Objective: The aim of the present study was to perform the mutational screening of PARK2 gene and dopamine level in PD patients of Coimbatore population,…Combination Antiretroviral therapy (cART)-induced cerebellar and prefrontal cortex disorders: A Study on the impact of Naringenin and Quercetin
Objective: This study was designed to investigate the therapeutic potential of selected bioflavonoids on cART-induced neurological disorders. Background: Long term usage of combination antiretroviral therapy…Identification of genetic alterations and SNCA mutation in Parkinson’s disease patients of Coimbatore Population, India
Objective: The aim of the study is to analyze the genetic alterations in SNCA gene and dopamine transporter in 22 PD patients of Coimbatore population.…
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