Dysregulations of GABAergic neurotransmission in Huntington’s disease brain
Objective: To investigate (1) the expression of GABAA receptors and KCC2 in both Huntington's disease (HD) mouse models and patients and (2) the inhibitory effect…Cerebellar GABA in essential tremor and dystonic tremor: A MR spectroscopy study
Objective: To explore the role of GABA in the pathophysiology of ET and DT by using MR spectroscopy. Background: The mechanisms of tremor in ET…Motor cortex neuroplasticity and learning following high-intensity interval exercise
Objective: To determine the effect of high-intensity interval (HIT) exercise on motor cortex plasticity and learning in healthy young adults. Background: Motor skill learning requires…Cerebellar GABA-A receptor activity is inversely correlated with gait speed in Parkinson’s disease
Objective: To investigate the relationship between regional cerebral expression of benzodiazepine receptors and gait speed in Parkinson's disease (PD). Background: Flumazenil is a short-acting intravenously…Dopaminergic medication affects choice bias in Parkinson’s disease
Objective: Assess dopaminergic effects on choice bias in Parkinson's disease (PD). Background: Bradykinesia, rigidity and resting tremor are the core symptoms of PD, but many…Does repetitive transcranial magnetic stimulation (rTMS) affect cognitive function in Parkinson’s disease by modulating high-frequency brain oscillations: A magnetoencephalography (MEG) study
Objective: To better understand the mechanisms of how repetitive transcranial magnetic stimulation (rTMS) may improve cognitive function in Parkinson's disease (PD). Background: Cognitive dysfunction and…Therapeutic potential of compounds preferring specific GABAA receptor subunits for the treatment of dystonia?
Objective: To further define the pathophysiology of the reduction of striatal interneurons in an animal model of dystonia and to develop novel therapeutic strategies targeting…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.