Post-Covid-19 Parkinson’s disease: a Brazilian case series.
Objective: To describe two patients with post-COVID-19 Parkinson’s disease (PD) and discuss their possible causes. Background: PD is a neurodegenerative disorder characterized by motor and…Ultrastructural Characterization of Monocytes in Parkinson’s Disease and GBA mutations
Objective: To identify morphological changes in circulating CD14+ monocytes in manifesting and non-manifesting carriers of mutations of the GBA gene and Parkinson’s disease (PD). Background: Mutations of…Mutations in GBA and LRRK2 are not associated with increased inflammatory markers
Objective: To assess central and peripheral cytokines among Parkinson's disease (PD) patients with mutations in the LRRK2 and GBA genes as well as among non-manifesting…Integrated Multi-omics of the Gut Microbiome Reveal 2-Hydroxypyridine as a Novel Molecule Relevant to Parkinson’s Disease Pathogenesis
Objective: To search for molecular links between Parkinson’s disease (PD) pathogenesis and gut microbes based on integrated multi-omic analyses of fecal samples from patients with…Targeted plasmaproteome identifies a distinct biomarker panel in early and prodromal Parkinson’s disease
Objective: To identify protein biomarkers in plasma of patients with Parkinson’s disease (PD). Background: Inflammation plays a key role in the initiation and progression of…The gut microbiome in Parkinson’s disease: longitudinal insights into disease progression and the use of device-assisted therapies.
Objective: We investigated the temporal stability of gut microbiome (GM) profiles from Parkinson’s disease (PD) patients initiating device-assisted therapies (DAT) and in a separate cohort…Gut microbiota and nutritional profiles of Parkinson’s disease patients.
Objective: We investigated the gut microbiome (GM) composition in association with various clinical features and nutritional data in a large cross-sectional Australian Parkinson’s disease (PD)…Development and validation of a profile of peripheral immune biomarkers for Parkinson’s disease: A multicenter, retrospective study
Objective: This multicenter study was designed to investigate the association between multiple peripheral immune biomarkers and the risk of Parkinson’s disease (PD). Background: Several studies…Predicting the effects of Tumor Necrosis Factor inhibition on the risk and age at onset of Parkinson’s disease: A Mendelian randomization study
Objective: To evaluate whether inhibition of Tumor Necrosis Factor (TNF) signaling may reduce the risk of Parkinson’s disease (PD) and/or delay onset of PD. Background:…Neuroinflammation and Myelin changes in MSA-P evaluated using Advanced Diffusion MRI and Myelin Sensitive Imaging Techniques
Objective: To determine more specific neuropathologies of the white matter in patients with multiple system atrophy-parkinsonian variant (MSA-P) using multi-shell diffusion magnetic resonance imaging (MRI)…
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