Occurrence of brain capillary dysfunction in patients with REM sleep behavior disorder
Objective: To assess whether changes in brain capillary function measured with magnetic resonance imaging (MRI) can be detected in patients with REM sleep behavior disorder…Balance training modulates the concentration of pro- and anti-inflammatory cytokines in the plasma of elder people and PD patients. A pilot study
Objective: Assessment as to whether moderate intensity systematic balance training (BT) affects the level of IL-10, IL-6 and TNF-α in healthy, elder people and in…18F-DPA714 PET reveals neuroinflammatory activity in the Substantia nigra of patients with Parkinson disease
Objective: We investigated whether 18F-DPA714 imaging could be a sensitive marker of neuroinflammation in Parkinson disease (PD). We took into account the polymorphism of TSPO…Inflammatory cytokines in Saudi Parkinson cohort
Objective: To identify inflammatory diagnostic and prognostic biomarkers for PD in serum. Background: Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's…Cortical cholinergic dysfunction correlates with microglial activation in the Substantia Innominata in patients with REM sleep behavior disorder
Objective: To explore possible correlations between levels of microglial activation (neuroinflammation) in the Substantia Innominata (SI), the major source of cholinergic input to the cortex,…Plasma membrane Ca2+ Atpase 1 as a candidate to mediate the degeneration of dopaminergic neurons by inflammation in Parkinson’s disease
Objective: To identify genes involved in the degeneration of the dopaminergic neurons (DN) of the substantia nigra (SN) by inflammation. Background: Parkinson’s disease (PD) is…Evaluation of Imidazoline 2 binding sites reflecting astroglia pathology in Parkinson’s Disease: An in vivo [11C]BU99008 PET study
Objective: We aimed to evaluate the role of astroglia activation in Parkinson's disease (PD) using [11C]BU99008 PET, a novel radioligand with high specificity and selectivity…Gut Feelings about Parkinson’s Disease: The Influence of the Gut Microbiota in a Rodent Model
Objective: The objective of this study was to investigate the gut microbiota in a pilot cohort of Australian patients with PD, and a rodent model…Evaluation of Imidazoline 2 binding sites reflecting astroglia pathology in Huntington’s Disease: An in vivo [11C]BU99008 PET study
Objective: We aimed to evaluate the role of astroglia activation in Huntington’s disease gene expansion carriers (HDGECs) using [11C]BU99008 PET, a novel radioligand with high specificity and…Long-Term Effects of LPS and Alcohol in Rats: A Model of Neuro-Degenerative Disease
Objective: We postulate alterations of the intestinal barrier (or leaky guts) enhances inflammation, as well as the production of alpga (α)-synuclein which has characteristic pathological…
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