Phosphorylation by GSK-3β enhances binding of metal ion induced tau oligomers to neutral lipid surfaces
Objective: To dissect the complex interplay of tau hyperphosphorylation, metal ion induced oligomer formation and membrane interactions applying single particle fluorescence techniques. Background: Fibrillar deposits…Relationship of serum ferritin level and tic severity in children with Tourette syndrome
Objective: Evaluate the relationship between serum ferritin levels and tic severity, as well as consequent impact on life, in children with Tourette Syndrome. Background: There…Iron accumulation and volume loss in the extrapyramidal motor system in Friedreich ataxia: The IMAGE-FRDA study
Objective: To examine whether iron dysregulation and neurodegeneration influences the motor system outside of the cerebellum in Friedreich ataxia (FRDA). Background: FRDA is an autosomal…Iron accumulation in a Wilson disease patient: Longitudinal 7T MRI and transcranial sonography study
Objective: To investigate longitudinal changes in clinical symptoms, 7T MRI and transcranial sonography (TCS) during chelating treatment in a Wilson disease (WD) patient. Background: Pathophysiological…Transcranial sonography of the substantia nigra and its correlation with iron metabolism and c-reactive protein in Parkinson’s disease
Objective: To measure the echogenicity of the substantia nigra (SN) by transcranial sonography (TCS) in PD patients and discuss its correlation with iron metabolism and…Brain iron levels in Parkinson’s disease by postmortem and MRI measurements: A systematic review and meta-analysis
Objective: In this study we performed a systematic review and meta-analysis aiming to understand PD-associated iron variations in all brain regions that have been examined,…MRI signatures of the brain of Parkinson’s disease and idiopathic REM sleep behavioral disorder subjects
Objective: To characterize brain microstructural integrity, iron loads, and functional connectivity in 10 idiopathic rapid eye movement sleep behavior disorder (RBD), 10 Parkinson's disease (PD)…Magnetic resonance imaging of nigrosome-1 in the diagnosis of early Parkinson’s: Initial results of the Parkinson’s magnetic imaging repository (PaMIR)
Objective: To evaluate the accuracy of T2* weighted high resolution 3T Magnetic Resonance Imaging (MRI) in the diagnosis of Parkinson's disease (PD) in a prospective…In vivo MRI detection of Parkinson’s disease associated degeneration in the lateral ventral tier of substantia nigra pars compacta
Objective: To test a novel multimodal MRI approach for in vivo assessment of the subregion of substantia nigra pars compacta (SNpc) most vulnerable to Parkinson's…Glial cells and iron accumulation in the brain of the Zitter rat
Objective: To investigate relationship between glial cell and iron accumulation in the brain of the Zitter rat, which is one of neurodegenerative disease model. Background:…
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