Motor Fluctuations in Parkinsons Disease and their Correction
Objective: To evaluate the frequency of motor fluctuations in patients with Parkinson's disease and to study the effectiveness of methods modifying the course of the…The role of serotonergic mechanisms in the formation of levodopa-induced drug-induced dyskinesias in Parkinson’s disease
Objective: To study the quantitative content of serotonin and dopamine in the blood plasma of patients with Parkinson's disease and to conduct a clinical and…Safety and Effectiveness of Co-careldopa for Motor Recovery in Post-Stroke Patients: A Systematic Review
Objective: To examine the safety and efficacy of co-careldopa for motor recovery in post-stroke patients. Background: The use of co-careldopa for improving motor function in…Effect of Continuous Subcutaneous Infusion of Foslevodopa/Foscarbidopa on motor fluctuations, dyskinesia, and sleep; subjective vs. PKG watch recordings.
Objective: To evaluate the impact of continuous subcutaneous infusion (CSCI) of foslevodopa/foscarbidopa on bradykinesia, dyskinesia, and sleep quality using self-reported Hauser diaries and Parkinson’s KinetiGraph…Individual physiomarkers of levodopa-induced local field potential fluctuations interact with deep brain stimulation in Parkinson’s disease
Objective: We investigated the behavior of LFPs in 57 patients across therapeutic states using a data-driven method to find personalized physiomarkers. Background: The power of…Assessment of Hypomimia in Parkinson’s Disease
Objective: To compare spontaneous facial expression of Happiness as measured by Action Units; AU6 (cheek raise) and AU12 (smile) between individuals with Parkinson’s Disease (PD)…IPX203 (ER CD-LD) super-responders: Description of a patient subpopulation reaping extra benefits in dose-response when converting from IR CD-LD
Objective: To generate quantitative data helping dose optimization when converting Parkinson’s disease (PD) patients from IR CD-LD to IPX203. Background: IPX203 is the first extended-release…Gastrointestinal Dysfunction and Levodopa Therapeutic Response in Parkinson’s Disease: A Brazilian Cross-sectional Study
Objective: To investigate the relation between constipation and the onset time of levodopa therapeutic effect in Parkinson's disease (PD). Background: Levodopa therapeutic response depends on…Dopamine replacement therapy modulates dopa decarboxylase, prolactin and AOC3 levels in Parkinson’s disease
Objective: Investigate the impact of dopamine replacement therapy (DRT) on the serum and CSF proteome of people with Parkinson’s disease (PwPD). Background: New high-throughput technologies…Nutritional Parameter Changes in Parkinson’s Disease Patients Receiving Continuous Subcutaneous Infusion of Foslevodopa-Foscarbidopa
Objective: This study aims to assess changes in nutritional parameters in patients with Parkinson’s disease (PD) undergoing continuous subcutaneous infusion (CSCI) of foslevodopa-foscarbidopa. Background: Device-aided…
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