MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Magnetic resonance imaging(MRI)"

  • MDS Virtual Congress 2021

    Developing 31-phosphorus magnetic resonance spectroscopy (31P-MRS) as an imaging biomarker to identify mitochondrial dysfunction in Parkinson’s disease

    T. Payne, M. Sassani, S. Roscoe, S. Bradley, A. Anton, E. Reed, I. Wilkinson, H. Mortiboys, T. Jenkins, O. Bandmann (Sheffield, United Kingdom)

    Objective: To determine if 31P-MRS can identify mitochondrial dysfunction in-vivo and if this correlates with in-vitro measures of mitochondrial function obtained from patient derived fibroblasts…
  • MDS Virtual Congress 2021

    Brain MRI morphological changes in different self-reported sleep disturbances in PD patients

    X. Ma, W. Su, H. Chen (Beijing, China)

    Objective: Our study explored associations between a variety of sleep-related problems and grey matter alterations in PD. Background: Sleep disturbance is a common non-motor feature…
  • MDS Virtual Congress 2021

    Brain MRI Cortical Atrophy correlation to clinical onset in Huntington’s Disease

    H. Estrada-Rodriguez, JD. Garcia-Romero, MA. Muñuzuri-Camacho, RA. Abundes-Corona, DD. Vásquez Guevara, LM. Gaibor Noboa, A. Cervantes-Arriaga, M. Rodriguez-Violante (Mexico City, Mexico)

    Objective: To describe brain Magnetic Resonance Imaging (MRI) characteristics in Latin American individuals with Huntington's Disease (HD) and to correlate them to major symptom at…
  • MDS Virtual Congress 2021

    Cortical microstructural alterations are more sensitive than morphology changes to cortical degeneration in Parkinson’s disease with mild cognitive impairment

    X. Bai, T. Guo, X. Guan, C. Zhou, J. Wu, M. Zhang (Hangzhou, China)

    Objective: To compare the sensitivity of detection cortical degenerative changes in patients with Parkinson’s disease (PD) and mild cognitive impairment (MCI) between the diffusion magnetic…
  • MDS Virtual Congress 2021

    Resting state functional connectivity networks related to MDS-UPDRS motor outcomes in Parkinson’s Disease

    A. Ragothaman, M. Mancini, J. Nutt, D. Fair, O. Miranda-Dominguez, F. Horak (Portland, USA)

    Objective: Investigate the functional connectivity network pairs associated with the motor symptoms in people with Parkinson’s disease (pwPD). Background: PD is a neurodegenerative disorder primarily…
  • MDS Virtual Congress 2021

    Total cerebral small vessel score associated with Hoehn and Yahr stages in Parkinson’s disease

    X. Ma, W. Su, H. Chen (Beijing, China)

    Objective: To evaluate the total cerebral small vessel disease (CSVD) score in patients with Parkinson’s disease at different stages and its related factors. Background: Parkinson’s…
  • MDS Virtual Congress 2021

    Evolving inclusion criteria in early manifest Huntington’s disease (HD) to address striatal atrophy: Lessons from HD-GeneTRX-1, the first gene therapy trial

    E. Furr-Stimming, C. Testa, P. Larson, C. Ross, R. Lonser, A. Samii, D. Cooper, S. Ying, M. Clarkin, E. Sawyer, R. Reilmann (Houston, USA)

    Objective: To describe the early screening experience and evidence-based adaptations to the inclusion criteria for HD-GeneTRX-1 (NCT04120493). Background: AMT-130 is an AAV5-based gene therapy intended…
  • MDS Virtual Congress 2021

    EVALUATION OF THE ABSENCE OF NIGROSOME 1 BY MAGNETIC RESONANCE 3 TESLA IN PARKINSON’S DISEASE ACCORDING TO TIME OF EVOLUTION TO DIAGNOSIS VS MESENCEPHALIC ECOGRAPHY.

    J. Bestoso, L. Ciancaglini, C. Stefani, F. Silveira, M. Pérez Akly, J. Norscini, J. Funes, C. Besada, D. Bauso (Buenos Aires, Argentina)

    Objective: The primary objective was to evaluate the absence of nigrosome 1 in 3TMRI in a group of patients with PD according to their evolutionary…
  • MDS Virtual Congress 2021

    Cognition-related functional topographies in Parkinson’s disease: Localized loss of the ventral default mode network

    K. Schindlbeck, A. Vo, P. Mattis, K. Villringer, F. Marzinzik, J. Fiebach, D. Eidelberg (Manhasset, USA)

    Objective: We sought to determine whether functional network abnormalities seen in patients with Parkinson’s disease (PD) and cognitive decline reflect the loss of the default…
  • MDS Virtual Congress 2021

    Expanding the phenotypic spectrum of diabetic striatopathy: a case series

    N. Chunga, G. Schifitto, R. Ramchandran, A. Lang, K. Lizarraga (Rochester, USA)

    Objective: To illustrate the spectrum of diabetic striatopathy by presenting 3 cases with different clinical and neuroimaging findings. Background: Diabetic striatopathy is a rare complication…
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