Pantothenate kinase-associated neurodegeneration in Tunisian families
Objective: To describe clinical features, imaging and genetic findings of 6 Tunisian families diagnosed with PKAN. Background: Pantothenate kinase-associated neurodegeneration (PKAN) is an autosomal recessive…Usefulness of Cardiac MIBG Scintigraphy, DAT scan and midbrain/pontine ratio to differentiate Parkinson disease from atypical parkinsonian syndrome
Objective: The purpose of this study was to evaluate the usefulness of cardiac 123I-metaiodobenzylguanidine (MIBG) uptake, Dopamine transporter (DAT) scan and midbrain/pontine ratio (M/P ratio)…Multimodal Graph Theory Analysis Identifies Reward Network in Prediction of Motor Response to Deep Brain Stimulation
Objective: Identify structural and functional networks that may be used to predict motor improvement after deep brain stimulation (DBS), supporting the existence of an underlying…Classification of spinocerebellar degeneration based on ratio of brainstem white matter to cerebellar gray matter by voxel-based morphometry
Objective: We examined the usefulness of voxel-based morphometry (VBM) analysis in auxiliary diagnosis of cases with spinocerebellar degeneration, including those with MSA-C. Background: In Japan,…Aberrant structural connectivity of the executive network in Progressive Supranuclear Palsy
Objective: To ascertain the structural connectivity of the executive network in progressive supranuclear palsy (PSP) using probabilistic tractography. Background: Cognitive deficits are highly prevalent in…Distinct neuronal correlates underpin impulsive action and impulsive choice in Tourette disorder
Objective: (i) Evaluate cognitive impulsivity in Tourette disorder (TD), (ii) identify neuronal correlates of cognitive impulsivity. Background: TD is characterized by motor and vocal tics,…Characteristics of the clinical and cerebral metabolism in Parkinson’s disease with atrophy in nucleus basalis of Meynert
Objective: We investigated characteristics of clinical and cerebral glucose metabolic abnormalities in Parkinson’s disease (PD) with atrophy in the nucleus basalis of Meynert (NBM). Background:…Changes in Neuromelanin MRI Signal in Parkinson’s Disease: A Longitudinal Study
Objective: To investigate the neuromelanin (NM) signal changes in Parkinson’s disease (PD) patients associated with disease progression. Background: PD is characterized by the progressive loss…Structural connectivity changes in G2019S-LRRK2 gene mutation carriers without manifest Parkinson’s disease
Objective: We hypothesised that abnormal sprouting of serotonergic terminals in the hypothalamus may lead to abnormal structural connectivity, which can be measured with diffusion tensor…Imaging Parkinson’s disease pathology: A comparison between neuromelanin-sensitive MRI, susceptibility weighted imaging and [11C]PE2I DAT PET
Objective: We compared 2 novel MRI techniques: neuromelanin-sensitive MRI (NM-MRI) and susceptibility weighted imaging (SWI) with [11C]PE2I PET in order to establish their validity as biomarkers…
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