Aberrant structural connectivity of the executive network in Progressive Supranuclear Palsy
Objective: To ascertain the structural connectivity of the executive network in progressive supranuclear palsy (PSP) using probabilistic tractography. Background: Cognitive deficits are highly prevalent in…Distinct neuronal correlates underpin impulsive action and impulsive choice in Tourette disorder
Objective: (i) Evaluate cognitive impulsivity in Tourette disorder (TD), (ii) identify neuronal correlates of cognitive impulsivity. Background: TD is characterized by motor and vocal tics,…Characteristics of the clinical and cerebral metabolism in Parkinson’s disease with atrophy in nucleus basalis of Meynert
Objective: We investigated characteristics of clinical and cerebral glucose metabolic abnormalities in Parkinson’s disease (PD) with atrophy in the nucleus basalis of Meynert (NBM). Background:…Changes in Neuromelanin MRI Signal in Parkinson’s Disease: A Longitudinal Study
Objective: To investigate the neuromelanin (NM) signal changes in Parkinson’s disease (PD) patients associated with disease progression. Background: PD is characterized by the progressive loss…Structural connectivity changes in G2019S-LRRK2 gene mutation carriers without manifest Parkinson’s disease
Objective: We hypothesised that abnormal sprouting of serotonergic terminals in the hypothalamus may lead to abnormal structural connectivity, which can be measured with diffusion tensor…Imaging Parkinson’s disease pathology: A comparison between neuromelanin-sensitive MRI, susceptibility weighted imaging and [11C]PE2I DAT PET
Objective: We compared 2 novel MRI techniques: neuromelanin-sensitive MRI (NM-MRI) and susceptibility weighted imaging (SWI) with [11C]PE2I PET in order to establish their validity as biomarkers…Braak model in Parkinson disease using MRI biomarkers
Objective: The aim of this study was to test using multimodal MRI biomarkers if the pattern of neurodegeneration in the brain of patients with PD…MCI reverters have a favorable cognitive prognosis and cortical integrity in Parkinson’s disease
Objective: To investigate whether reversion to cognitively normal status (CogN) is clinically relevant in Parkinson’s disease with mild cognitive impairment (PD-MCI). Background: The concept of…Structural connectome of brainstem nuclei in REM sleep behavior disorder, a model of premanifest synucleinopathy
Objective: To investigate in vivobrainstem structural connectivity changes in a model of premanifest synucleinopathy, REM sleep behavior disorder (RBD), using 7 T high spatial-resolution diffusion-tensor-imaging (DTI)…Longitudinal Analysis of the Corticospinal tract microstructure in Parkinson’s Disease Patients
Objective: To assess longitudinal abnormlities throughout the corticospinal tract in Parkinson’s Disease patients. Background: Parkinson’s Disease (PD) is a neurodegenerative progressive disease might become a pandemic…
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