Complementary value of MRI-based differential diagnosis in parkinsonism
Objective: We aimed to evaluate the complementary diagnostic values of MRI characteristics to differentiate various types of parkinsonism. Background: Although precise differential diagnosis of parkinsonism…Decreased amyloid-beta in patients with Idiopathic Parkinson’s Disease and white matter hyperintensities
Objective: The aim of this study is to investigate the clinical and biochemical profile of patients with PD with and without WMH. Background: Parkinson’s disease…Diagnostic potential of automated middle cerebellar peduncle volumetry in variants of multiple system atrophy
Objective: To include probabilistic information on the location of the middle cerebellar peduncle (MCP) into an existing subcortical segmentation atlas and to evaluate the diagnostic…Cerebrospinal fluid flow dynamics in Huntington’s disease evaluated by phase contrast MRI
Objective: To elucidate the dynamics of CSF flow through the neuraxis in Huntington’s disease (HD) using phase contrast magnetic resonance imaging (PCMRI). Background: HD is…Exploring novel diffusion-derived biomarkers in Parkinson’s disease Freezing of Gait
Objective: To explore the association between novel diffusion-derived structural imaging biomarkers and disease duration in Parkinson’s disease with freezing of gait (PD-FOG). Background: Increasing free-water…Discriminating Idiopathic PD Patients and Controls in PPMI Using Integrative Multi-Modal Neuroimaging Analysis with Graph Convolutions
Objective: To discriminate Parkinson’s disease (PD) patients and controls in the Parkinson’s Progression Markers Initiative (PPMI) cohort according to MRI features using a novel a…Brain Perfusion pattern linked to depressive state in Parkinson’s: An arterial spin labelling MRI study
Objective: To investigate patterns of cerebral blood flow alteration associated with depressive state in Parkinson’s disease (PD) by using principal component analysis of arterial spin…Cortical thinning as a neuroimaging marker of cognitive decline in X-linked dystonia-parkinsonism
Objective: To investigate whether alterations of cortical thickness correspond to cognitive dysfunction in XDP patients. Background: X-linked dystonia-parkinsonism (XDP) is a severe, hereditary movement disorder…Quantitative Midbrain Measurement in Diagnosing Variants of Progressive Supranuclear Palsy
Objective: To evaluate the effectiveness of quantitative midbrain measurements in differentiating vPSP from multiple system atrophy (MSA) and Parkinson’s disease (PD). Background: Newly published criteria…Olfactory dysfunction, sleep disturbances, neuronal loss, and regional brain atrophy in an inducible mouse model of Alpha-Synucleinopathy
Objective: The objective of this work is to develop a unique mouse model of spreading α-synucleinopathy to accelerate the development of novel disease-modifying treatments for…
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