Action verb use in PD: A challenge to the embodied cognition hypothesis?
Objective: To characterize action verb production in Parkinson's disease (PD) during a picture description task, and evaluate associations with motor and cognitive function. Background: The…A mouse model to test the cortical pathogenic theory of Parkinson’s disease
Objective: To develop a mouse model of chronic corticostriatal overactivity and increase expression of corticostriatal alpha-synuclein. Background: Parkinson’s disease typically has a focal motor onset1,…Cortical and cerebellar excitability in essential tremor
Objective: To investigate the functional state of motor cortex excitability and the involvement of the cerebello-thalamo-cortical pathway using transcranial magnetic stimulation (TMS) in patients with…Reducing corticospinal excitability with transcranial static magnetic field stimulation
Objective: To investigate the potential of transcranial static magnetic field stimulation (tSMS) for reducing corticospinal excitability when delivered to the primary motor cortex (M1) or…Home-based transcranial static magnetic field stimulation of the motor cortex for treating levodopa-induced dyskinesias in Parkinson’s disease
Objective: To investigate the potential of transcranial static magnetic field stimulation (tSMS) as a non-pharmacological, non-invasive, home-based treatment to manage levodopa-induced dyskinesias (LIDs) in Parkinson’s…Pallidal deep brain stimulation entrains finely tuned gamma oscillations in motor cortex
Objective: Determine whether therapeutic pallidal deep brain stimulation can entrain finely tuned gamma oscillations in the motor cortex. Background: In Parkinson’s disease (PD), finely tuned…Maladaptive motor cortex plasticity off medication in Parkinson’s disease patients with levodopa-induced dyskinesias
Objective: To test the hypothesis that motor cortex plasticity is maladaptive in Parkinson's disease (PD) patients suffering from dyskinesias, as compared to non-dyskinetic patients. Background:…A Patient with Gait Disturbance Caused by Parkinson’s Disease: A Case Report
Objective: It is well known that mental simulation of movement in the brain can facilitate motor rehabilitation. Our hypothesis is: can a direct, sequential stimulation…Left-right motor cortex asymmetry in the pathophysiology of essential tremor
Objective: To investigate left-right motor cortex asymmetry in the pathophysiology of essential tremor (ET). Background: ET is typically bilateral but usually manifests with mild asymmetry…7 Tesla MRI investigation of cortical thickness in patients with Huntington’s disease and age-matched healthy controls
Objective: Evaluate cortical thickness in Huntington's disease (HD) using 7 Tesla (T) MRI. Background: There are currently no effective disease-modifying therapies for HD. In order…
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