Serum Biomarker Profiles in Adolescents with Type 1 Diabetes-Associated Dystonia: The Role of Neurofilament Light Chain and Metabolic Indices
Objective: To evaluate the relationships between serum neurofilament light chain (NfL), homocysteine (Hcy), glycated hemoglobin (HbA1c), folic acid, and vitamin B12, and their impact on…Evaluation of Electromyographic Measures of Cervical Dystonia Using a 12-Muscle Recording Paradigm
Objective: We evaluated the presence of these features across a set of 12 cervical muscles predominantly associated with abnormal posturing in CD using a multi-muscle…Data Driven Clinical Insights from Longitudinal Cloud-Aggregated Neural Data to Inform a Real-World Adaptive DBS Programming
Objective: Characterize clinical workflow insights gained from expanded access to neural data via a cloud connected platform in adaptive DBS. Background: Adaptive deep brain stimulation…Intranasal Delivery of Berberine-Loaded Solid Lipid Nanoparticles Ameliorates Neuropathological and Behavioral Deficits in a Preclinical Alzheimer’s Model
Objective: To evaluate the pharmacokinetic profile and neuroprotective efficacy of intranasally administered berberine-loaded solid lipid nanoparticles (BE-SLN) in a streptozotocin (STZ)-induced rat model of Alzheimer’s…Dopamine and Na,K-ATPase: Mechanisms of Direct Enzyme Modulation in the Hippocampus
Objective: This study aimed to investigate the direct effect of dopamine on Na,K-ATPase activity in rat hippocampal membranes and to determine whether this effect depends…Early impairment in iTBS-induced cortical plasticity in drug-naïve Parkinson’s disease: a rTMS pilot study
Objective: To characterize the pattern and temporal evolution of iTBS-induced LTP-like cortical plasticity in drug-naïve patients with early Parkinson’s disease (PD). Background: Long-term potentiation (LTP)-like…Monopolar Sensing within the Globus Pallidus and the Relationship between Clinical Outcomes and Anatomy
Objective: This study aims to understand how results from monopolar sensing of local field potential (LFP) beta power can better support more efficient programming of…Movement Neurophysiology Studies: Clinical Practice Patterns and Standardization
Objective: Create standardized procedures or movement neurophysiology studies (MNS). Background: Movement neurophysiology studies (MNS) with surface electromyography (EMG), accelerometers, and other tools have established clinical…Temporal Prediction and Multisensory Integration in Musician’s Dystonia
Objective: We aimed to determine whether temporal prediction and multisensory integration are altered in musician’s dystonia (MD) and whether task-specific visual, auditory, and audiovisual cues…Delineating Therapeutic and Non-therapeutic Neural Signatures of Deep Brain Stimulation
Objective: To develop an information-theoretic framework that identifies neural signatures predicting therapeutic benefit, independent of stimulation artifacts, enabling objective DBS parameter optimization. Background: DBS programming…
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