Decoding Deep Brain Activity from Cortical Signals using Deep Learning across Movement Disorders
Objective: To develop and validate a deep learning framework for reconstructing subcortical neural activity from cortical electrocorticography (ECoG), enabling continuous deep brain biomarker inference without…Beyond the “best contact”: correlation of ai-guided dbs contact distribution and subthalamic nucleus beta physiology in parkinson’s disease patients
Objective: We hypothesized that optimal stimulation setting may involve a muti-contact configuration rather than a single contact with the largest therapeutic window (TW). We aimed…Drivers of Navigated Walking Performance in Aging and Parkinson’s Disease: Insights From Behavioral Clustering, Clinical and Neuroimaging Data
Objective: Identify and characterize patterns of navigated walking performance in people with PD (Parkinson’s disease) and healthy adults, by means of data-driven cluster analysis. Background:…Toward Objective Monitoring of Motor Fluctuations in Parkinson’s Disease: TMS-EEG Biomarkers
Objective: Assess utility of TMS-EEG as objective markers for Motor fluctuations (MF) in Parkinson’s disease (PD). Background: MF in PD are episodic changes in motor…Adaptive Deep Brain Stimulation in Parkinson Disease: Preliminary Single-Center Results
Objective: To describe initial outcomes of alpha-beta (8-30Hz)-guided subthalamic nucleus (STN) adaptive deep brain stimulation (aDBS) in Parkinson disease (PD) in a single-center cohort. Background:…Objective profiling of parkinsonian and essential tremor using EMG and accelerometry
Objective: To determine whether electrophysiological features derived from EMG and accelerometry can distinguish PD tremor from ET. Background: Clinical differentiation between tremor in Parkinson’s disease…Burst versus Conventional Deep Brain Stimulation Engage Distinct Cortico-Subthalamic Circuit Dynamics in Parkinson’s Disease
Objective: To characterize the neural effects of burst DBS (bDBS) on cortico-subthalamic circuit dynamics in Parkinson’s disease (PD) and determine whether they differ from conventional…A Novel paradigm for the recording of col-cap movements and muscle activity in Cervical Dystonia
Objective: We developed a protocol combining multi-muscle surface electromyography (sEMG) and kinematic analysis to characterise cervical muscle activity and head-neck-trunk movement patterns in CD after…Serum Biomarker Profiles in Adolescents with Type 1 Diabetes-Associated Dystonia: The Role of Neurofilament Light Chain and Metabolic Indices
Objective: To evaluate the relationships between serum neurofilament light chain (NfL), homocysteine (Hcy), glycated hemoglobin (HbA1c), folic acid, and vitamin B12, and their impact on…Evaluation of Electromyographic Measures of Cervical Dystonia Using a 12-Muscle Recording Paradigm
Objective: We evaluated the presence of these features across a set of 12 cervical muscles predominantly associated with abnormal posturing in CD using a multi-muscle…
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