Quantifying the incremental burden of advancing Parkinson’s disease in patients meeting the “5-2-1” Criteria: Results from an international dataset from G7 countries
Objective: Quantify the incremental clinical and humanistic burden of advancing Parkinson’s disease (PD) in patients meeting the “5-2-1” criteria. Background: The burden of PD worsens…What can tell us Non-Motor Symptoms about Cognition and Gait in the Early Stage of PD Patients
Objective: To describe the motor, cognitive and non-motor profiles in the early stage of PD using eMotion Kinect system, Moca Test and PD-CRS. Background: The…Effect of regular practice of yoga versus aerobic exercise on motor and non motor signs and motor cortex plasticity in Parkinson’s disease
Objective: To test whether the regular practice of yoga (1) improves motor and non-motor symptoms and signs in Parkinson’s disease (PD) more than aerobic training…Urinary Symptoms and Parkinson’s Disease: The Patient’s Perspective
Objective: To learn about prevalence rates and the impact of urinary symptoms on day-to-day function and quality of life from the patient’s perspective. Background: Urinary…Cognitive pretesting of the Functional Rating Scale 2.0 for Huntington’s disease (FuRST 2.0): An iterative process
Objective: Develop a functional rating scale for Huntington’s disease (HD) using iterative rounds of cognitive pretesting (CPT). Background: We previously reported on focus group and…Increased neurofilament light chain plasma levels as a biological marker of mild cognitive impairment in Parkinson’s disease
Objective: To examine whether PD-MCI patients have increased plasma neurofilament light chain (NfL) levels compared to PD with normal cognition (PD-NC) and healthy controls (HC).…Non-Motor Fluctuations in Parkinson’s Disease (PD): Development and Validation of the Non-Motor Fluctuation Assessment Instrument (NoMoFA)
Objective: Validate and demonstrate reliability of the NoMoFA. Background: In patients with PD, sleep, mood, cognitive, autonomic and other non-motor symptoms (NMS) may fluctuate (NMF)…Dry Eye and Parkinson’s Disease: A Literature Review
Objective: To emphasize the dry eye diseases in Parkinson’s disease patients Background: In a patient with dry eye, ocular surface could have local inflammation and…Endorsement of self-reported non-motor symptoms is associated with higher self-rated motor experiences of daily living in MDS-UPDRS part 2 in Parkinson’s disease
Objective: To quantify the extent to which self-perceived motor limitations (MDS-UPDRS part 2) relate to self-reported levels of non-motor symptom severity. Background: The MDS-UPDRS part…Northwestern University Feinberg School of Medicine Parkinson’s disease and Movement Disorders Center Biorepository: bringing the clinic and lab together
Objective: To establish a biobank of DNA and tissue samples from a population of movement disorder patients, their family members and healthy controls recruited from…
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