Myocardial sympathetic denervation biomarkers for early detection of prodromal DLB
Objective: Because of the time course of detecting DLB symptoms and signs, DLB is poorly diagnosed and hardly differentiate from AD, especially in early stage…Genetics of Neurogenic Orthostatic Hypotension in Parkinson’s Disease
Objective: We examined the association between NOH and PD-related Single Nucleotide Polymorphism (SNPs) and mapped their effects on gene expression and metabolic and signaling pathways.…Incidence of orthostatic hypotension in Parkinson´s disease patients starting antiparkinsonian treatment
Objective: The main objetive of this study is to determine the percentage of patients diagnosed with Parkinson´s disease at Infanta Sofía University Hospital between september…Autonomic dysfunction in the early stages of atypical Parkinsonism would have the first approach in the diagnosis: A report of fifteen cases in the Mexican population.
Objective: This study describes the results of a complete autonomic evaluation in patients with Atypical Parkinsonism without a final diagnosis conclusion, performed in a Mexican…Supine hypertension is longitudinally associated with cognitive decline in Parkinson disease independent of orthostatic hypotension
Objective: To determine whether orthostatic hypotension (OH) and/or supine hypertension (SH) are longitudinally associated with cognitive decline in Parkinson disease (PD). Background: Cognitive impairment is…Orthostatic hypotension and frailty
Objective: to investigate the relationship between functional class of orthostatic hypotension (FC OH) and frailty index (FI). Background: frailty syndrome (FS) as well as orthostatic…Neurogenic orthostatic hypotension is not associated with generalized dysautonomia in early motor PD
Objective: We aim to assess the relationship between neurogenic Orthostatic Hypotension (nOH) and general dysautonomia in an early motor PD cohort. Background: Dysautonomia is a…Orthostatic vital sign changes do not influence 5-year motor outcomes in PD
Objective: We assessed whether orthostatic blood pressure (BP) and heart rate (HR) changes in an early motor PD cohort influence motor, and postural instability and…Neurogenic Orthostatic Hypotension in Parkinson’s Disease: Is there a role for Locus Coeruleus Magnetic Resonance Imaging?
Objective: To test whether degeneration of the Locus Coeruleus (LC) is associated with Orthostatic Hypotension (OH) in Parkinson’s disease (PD).To test whether degeneration of the…A multiple-dose thorough QT study to evaluate the effect of ampreloxetine on cardiac repolarization in healthy subjects
Objective: To characterize the effect of therapeutic and supratherapeutic doses of ampreloxetine on cardiac repolarization in healthy subjects. Background: Ampreloxetine is a potent NE reuptake…
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