Autonomic dysfunction in the early stages of atypical Parkinsonism would have the first approach in the diagnosis: A report of fifteen cases in the Mexican population.
Objective: This study describes the results of a complete autonomic evaluation in patients with Atypical Parkinsonism without a final diagnosis conclusion, performed in a Mexican…Supine hypertension is longitudinally associated with cognitive decline in Parkinson disease independent of orthostatic hypotension
Objective: To determine whether orthostatic hypotension (OH) and/or supine hypertension (SH) are longitudinally associated with cognitive decline in Parkinson disease (PD). Background: Cognitive impairment is…Orthostatic hypotension and frailty
Objective: to investigate the relationship between functional class of orthostatic hypotension (FC OH) and frailty index (FI). Background: frailty syndrome (FS) as well as orthostatic…Neurogenic orthostatic hypotension is not associated with generalized dysautonomia in early motor PD
Objective: We aim to assess the relationship between neurogenic Orthostatic Hypotension (nOH) and general dysautonomia in an early motor PD cohort. Background: Dysautonomia is a…Orthostatic vital sign changes do not influence 5-year motor outcomes in PD
Objective: We assessed whether orthostatic blood pressure (BP) and heart rate (HR) changes in an early motor PD cohort influence motor, and postural instability and…Neurogenic Orthostatic Hypotension in Parkinson’s Disease: Is there a role for Locus Coeruleus Magnetic Resonance Imaging?
Objective: To test whether degeneration of the Locus Coeruleus (LC) is associated with Orthostatic Hypotension (OH) in Parkinson’s disease (PD).To test whether degeneration of the…A multiple-dose thorough QT study to evaluate the effect of ampreloxetine on cardiac repolarization in healthy subjects
Objective: To characterize the effect of therapeutic and supratherapeutic doses of ampreloxetine on cardiac repolarization in healthy subjects. Background: Ampreloxetine is a potent NE reuptake…Levodopa-induced orthostatic hypotension in a large cohort of patients with Parkinson’s disease undergoing an acute levodopa challenge test
Objective: We aimed to investigate the frequency and associated risk factors for Levodopa-induced orthostatic hypotension (OH) in a large cohort of PD patients underwent acute…Impact of orthostatic hypotension with sleep disturbance on cognition
Objective: To define features of cognitive decline in a group of patients with orthostatic hypotension combined with sleep disorders. Background: recent data suggest that orthostatic…An Analysis of Subgroups of Multiple System Atrophy Patients from Ampreloxetine Phase 3 Trials
Objective: To present results in the subset of patients with multiple system atrophy (MSA) and relevant MSA subgroups from two ampreloxetine phase 3 trials for…
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