A Long-Term Safety, Tolerability, and Efficacy Study of Apomorphine Sublingual Film for On-Demand Treatment of “OFF” Episodes in Patients With Parkinson’s Disease: Interim Results
Objective: Evaluate the long-term safety (LTS), tolerability, and efficacy of apomorphine sublingual film (APL-130277; APL) for on-demand treatment of “OFF” episodes in patients with Parkinson’s…Baseline results of a virtual longitudinal, observational study of Parkinson’s disease: The AT-HOME PD cohort
Objective: To describe the baseline characteristics of Parkinson’s disease (PD) clinical trial participants enrolled in a remote, long-term observational follow-up study. Background: Participation in clinical…Daily Time-Course of Efficacy of Continuous Subcutaneous Infusion of Foslevodopa/foscarbidopa in Advanced Parkinson’s Disease Patients from a Phase 1b Study
Objective: Characterize and compare the time-course of Parkinson’s disease (PD) symptoms following 24h/day continuous subcutaneous infusion (CSCI) of foslevodopa/foscarbidopa and oral levodopa/carbidopa (LD/CD). Background: As…Patients’ Perceptions of Herbal Medicine for Parkinson’s disease: Thai Perspectives on Cannabis and Mucuna Pruriens
Objective: To determine patients’ perceptions and knowledge of herbal medicine, including medical cannabis (MC) and Mucuna pruriens (MP), for the treatment of Parkinson’s disease (PD) Background: The use…The Effect of Rasagiline on Motor and Non-Motor Symptoms in Parkinson’s Disease
Objective: In this study, we aimed to evaluate the effect of rasagiline treatment on motor and non-motor symptoms in patients with Parkinson’s disease (PD). Background:…Physiologically-based pharmacokinetic modeling of nilotinib to determine serum, cerebrospinal fluid, and brain exposures
Objective: To construct a physiologically-based pharmacokinetic (PBPK) model for predicting nilotinib pharmacokinetics (PK) in plasma and cerebrospinal fluid (CSF); and, to compare model-predicted serum and…Temporhythmal Correction: The New Way of Therapy and Diagnostic Secondary Vascular Parkinsonism
Objective: It is known that, in vascular parkinsonism (VP) and Parkinson’s disease (PD) it is observed shortening of steps, bradikinesia, oligokinesia, gait disorders and also…Association between Glutamic Acid Decarboxylase Antibodies (Anti-GADs) and Parkinsonism: Case Report
Objective: To make the first case report of the association between Anti-GAD and parkinsonism. Background: GAD (Glutamic Acid Decarboxylase) is the enzyme that catalyzes the synthesis of the…Correlation and comparison of the lipid profile and the body fat mass in people with Parkinson’s disease submitted to three physical therapies
Objective: To correlate and to compare changes on the lipid profile (LP) and on the body fat mass in people with Parkinson's disease (PD) submitted…Patients’ perspectives on shared decision-making in Parkinson´s disease
Objective: The aim of this study was to assess Parkinson’s disease (PD) patients’ preferences on how to take medical decisions. Background: Patients’ decisions are mainly…
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