A 3D CNN Approach for the Classification of Multiple System Atrophy using Multimodal Multicentric MRI
Objective: To automatically distinguish between healthy controls (HC) and patients with multiple system atrophy (MSA) with a completely automatic approach using a 3D convolutional neural…Association of β-Amyloid Load on PET with Cognitive Profiles Across the Lewy Body Diseases Continuum
Objective: To investigate the association between Aβ accumulation and clinical characteristics across the Lewy body disease (LBD) spectrum, with a specific focus on global and…Behind the wheel with Parkinson’s-Older patients’ review
Objective: To review characteristics of older Parkinson’s patients undergoing driving assessments presenting to Movements disorder’s clinic at Royal Berkshire Hospital, Reading,UK. Background: Parkinson’s leads to…Giant Aneurysm Causing Parkinsonism and REM Sleep Disorder
Objective: To describe a stepwise evaluation of a patient with a secondary parkinsonism that mimic idiopathic Parkinson´s Disease (PD). Background: PD clinically established encompasses the…Association Between Motor Symptoms and Autonomic Dysfunction in De Novo Parkinson’s Disease: Insights into the Role of the Gut-Brain Axis
Objective: This retrospective study aimed to investigate the relationship between motor symptoms and autonomic dysfunction in patients with de novo Parkinson's disease(PD). Background: Dysautonomia in…Patient-developed Unique Methods to Overcome Freezing of Gait in Parkinsonian Disorders
Objective: To present and share unique methods to overcome freezing of gait (FOG) in parkinsonian disorders. Background: Freezing of gait (FOG) is an episodic and…The Impact of VPS35 D620N Mutation on Alternative Autophagy and its Reversal by Estrogen in Parkinson’s Disease
Objective: We investigated the relationship between alternative autophagy and VPS35 D620N mutant-related PD pathogenesis. Background: VPS35 is critically involved in the mechanisms of neurodegeneration observed…Prolonged Positive Response: Subthalamic Nucleus as a Deep Brain Stimulation Target in X-linked Dystonia-Parkinsonism
Objective: To demonstrate long-term improvement of parkinsonism and dystonia in patients with X-linked dystonia-parkinsonism (XDP) following deep brain stimulation (DBS) in the subthalamic nucleus (STN).…Prevalence of Parkinson’s Disease and Possible Parkinsonian Syndrome in Gaucher Disease: Data From the ICGG Gaucher Registry
Objective: To estimate the age-specific risk of Parkinson’s disease (PD) and possible parkinsonian syndrome (pPS) in Gaucher disease (GD) based on registry data. Background: While…7year followup of Asia’s first case of sporadic ATP6AP2 Mutation: α-synucleinopathy or tauopathy?
Objective: ATP6AP2 mutation, previously described in literature to cause early onset Parkinson’s disease (PD) with atypical signs, evolved into frontotemporal lobar degeneration in a 7year…
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