Rethinking Parkinsonism: Limitations in Clinical Diagnosis
Objective: To highlight the limitations in clinically differentiating PD and MSA. Background: The antemortem differentiation of parkinsonian syndromes remains challenging due to overlapping symptomatology, particularly…Unveiling a rare case: Novel TBK1 variant presenting as Multiple system atrophy-like phenotype
Objective: Tumour necrosis factor NF-ƘB activator (TANK) binding kinase 1 (TBK1) is necessary for immune and inflammatory responses. Reports of TBK1 with neurodegeneration are noted…Beyond the Classic Triad: An Unusual Phenomenology of Parkinsonism in a Patient with Superficial Siderosis (SS)
Objective: To highlight the phenomenology in a complex case of superficial siderosis (SS) presenting with hearing loss, ataxia, and parkinsonism Background: SS is a rare…Impact of Cognition on Social Engagement in Community-based Older Adults with Parkinsonism
Objective: To investigate how cognition and gait influence social engagement in parkinsonism. Background: Social engagement is vital to quality of life in parkinsonism, yet the…Alpha-Synuclein Amplification Assays Utilizing Real-Time Quaking-Induced Conversion (RT-QuIC) from Non-Invasive Saliva as a Novel Diagnostic Tool for Patients with Parkinson’s Disease
Objective: The main objective is to evaluate the sensitivity of aSyn-RT-QuIC in diagnosing Parkinson's Disease (PD) from non-invasive saliva. The results will be corroborated in…A Tailored Approach to Parkinson’s Disease: The Influence of Hormonal Status in Women
Objective: To explore how reproductive health factors, such as menstruation and pregnancy, impact motor fluctuations in premenopausal women with young-onset idiopathic Parkinson’s disease (PD). Background:…A Multi-Transcriptional Risk Score Approach to Parkinson’s Disease Prediction
Objective: To improve the prediction of Parkinson’s disease (PD) by examining aggregate profiles of gene expression in the form of transcriptional risk scores (TRS). Background:…Impact of Stigma on Patients Diagnosed with Parkinson’s Disease in Buenos Aires (Argentina) : A Descriptive Study of Psychological, Occupational, and Social Dimensions
Objective: To assess the characteristics and impact of stigma in Parkinson’s disease (PD)patients and explore differences by age, gender, education level, and disease duration. Background: Stigma…The feasibility and practical utility of virtual visits for patients with Parkinson’s disease in different World Regions
Objective: To compare the access and visit quality/acceptability between in-office and virtual telemedicine visits for patients with Parkinson' s disease (PD) Background: Overcoming existing access…Atypical Parkinsonism in the Setting of Normal Pressure Hydrocephalus and a Colloid Cyst: Diagnostic Challenge
Objective: To present a case of atypical parkinsonism likely secondary to normal pressure hydrocephalus (NPH) and a colloid cyst at the foramen of Monro. Background:…
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