Subchronic copper exposure induces parkinsonism in rats: Neuromodulatory potential of curcumin
Objective: We aim herein to assess the effect of subchronic Cu-intoxication (0.125%) for 6 weeks on the dopaminergic, serotonergic and astroglial systems together with behavioral…Prevalence of orthostatic hypotension and postprandial hypotension in neurodegenerative diseases with synucleinopathy: a systematic review and meta-analysis
Objective: This study aimed to evaluate the prevalence of orthostatic hypotension (OH) and postprandial hypotension (PPH) in patients with Parkinson's disease (PD), multiple system atrophy…Cognitive impairment in patients with Parkinson’s Disease
Objective: The objective is to study the relation between cognitive impairment with the form and stage of PD. Background: Currently, there is a tendency of…Is DAT imaging abnormality in Normal Pressure Hydrocephalus always suggestive of degeneration? Evidences from three cases
Objective: To study parkinsonism in iNPH, in order to shed light on its pathogenesis, understand potential overlap with idiopathic parkinsonismsand its impact on the clinical outcome.…Periventricular hyperintensities and axial symptom of Parkinson’s disease
Objective: To investigate which area of white matter hyperintensities (WMH) is associated with motor symptom of Parkinson’s disease (PD) independently of dopaminergic depletion. Background: WMH…Structural connectivity changes in G2019S-LRRK2 gene mutation carriers without manifest Parkinson’s disease
Objective: We hypothesised that abnormal sprouting of serotonergic terminals in the hypothalamus may lead to abnormal structural connectivity, which can be measured with diffusion tensor…Evaluation of Imidazoline 2 binding sites reflecting astroglia pathology in Parkinson’s Disease: An in vivo [11C]BU99008 PET study
Objective: We aimed to evaluate the role of astroglia activation in Parkinson's disease (PD) using [11C]BU99008 PET, a novel radioligand with high specificity and selectivity…Transcranial Photobiomodulation as an adjunct to Levodopa therapy in patients with Parkinson’s Disease; an open label pilot study
Objective: To explore the effects of transcranial Photobiomodulation (tPBM) on symptoms of Parkinson's Disease and establish this therapy's efficacy as an adjunct to Levodopa. Background:…Diagnosing Dementia with Lewy Bodies – Characterizing the prevalence and underlying relationships between core and supportive clinical features
Objective: To characterize the interrelationship between core and supportive features of Dementia with Lewy Bodies, and identify optimal methods for their detection to inform better…Utilization of Monotherapy and Combination Therapies in Advanced Parkinson Disease Patients During Levodopa-Carbidopa Intestinal Gel Treatment from the COSMOS Study
Objective: Assess the percentages of advanced Parkinson’s disease (APD) patients treated with levodopa-carbidopa intestinal gel (LCIG) as a monotherapy or with add-on PD medications and…
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