L1CAM and TMEM119 enriched Exosomal markers in Parkinson’s Disease and Progressive Supranuclear Palsy: A Prospective Study
Objective: This study explored longitudinal changes in cellular inflammatory, autophagic mediators in L1CAM and TMEM119-enriched exosomal samples of patients with Parkinson’s disease (PD) and Progressive…Accuracy of the Tanner’s Questionnaire and the REM Sleep Behavior Disorder Single-Question Screen as Screening Tools for Parkinson’s Disease in a Brazilian Cohort
Objective: Assess the Tanner’s Questionnaire (TQ) and the REM Sleep Behavior Disorder Single-Question Screen (RBD1Q) performance as screening tools for Parkinson’s Disease (PD) in a…Differentiating Parkinsonism and related diseases by specific Parkinsonism patterns
Objective: This study aimed to identify characteristic parkinsonism patterns across PD, MSA and PSP, and evaluate their utility in early differentiation. Background: Parkinson's disease (PD), multiple…Evaluation of Nociception in a Model of Parkinson’s Disease for the Study of Non-Motor Symptoms in Trpv4-/- Animals
Objective: This study aimed to investigate the role of the TRPV4 receptor in regulating the nociception in a PD model experimental for the study of…Artificial Intelligence in the Early Detection of Parkinson’s Disease: Advances, Challenges, and Future Perspectives
Objective: This study reviews AI’s role in early PD detection, comparing AI-driven diagnostic methods with conventional clinical approaches in accuracy, reliability, and applicability. Background: Parkinson’s…Diagnostic yield of Whole-genome sequencing in Genetic Movement disorders
Objective: To assess the breadth of presentations to a tertiary neurogenetics clinic and evaluate the diagnostic yield of whole-genome sequencing (WGS) in genetic movement disorders.…Laryngeal Dystonia, Dopa-Responsive Parkinsonism and Primary Progressive Aphasia with Alzheimer Disease Pathology
Objective: To report a case of laryngeal dystonia (LD), parkinsonism and primary progressive aphasia (PPA) with Alzheimer disease (AD) pathology Background: The presence of 3-4 neurological…Drug-induced Parkinsonism Mimicking Parkinson´s Disease in Patients Treated with Flunarizine for Migraine
Objective: To understand the pattern of movement disorders caused by migraine prophylactic medicine such as flunarizine. Background: Migraine prophylactic treatments are usually taken for short…Analysis of the Association between SNCA Polymorphisms and the Risk of Multiple System Atrophy
Objective: To assess the impact of twenty-one single nucleotide polymorphisms (SNPs) located in different regulatory regions of the SNCA gene on the risk of developing…Retrospective Analysis of our Supportive Care Clinic and Lifestyle Improvement Fitness Program
Objective: The Supportive Care Clinic and Lifestyle Improvement Fitness (LIFT) program provides multidisciplinary care and online educational resources for our parkinsonian patients. Demographics of patients…
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