Effects of Handwriting Exercise on Functional Outcome in Parkinson’s Disease: A Randomized Controlled Trial
Objective: To determine whether handwriting exercise could improve writing skill and fine manual function in Parkinson’s disease (PD). Background: PD patients frequently experience micrographia, difficulty…Clinical Management of Incipient Wearing-off with the 19-Items Wearing off Questionnaire (WOQ-19)
Objective: To evaluate the use of the 19-items Wearing off Questionnaire (WOQ-19) to detect fluctuations in patients with non-advanced Parkinson's disease (PD) and to evaluate…Application of the “5-2-1” Screening Criteria in Advanced Parkinson’s Disease Patients Treated with Levodopa-Carbidopa Intestinal Gel: Interim Analysis from the DUOGLOBE Study
Objective: Evaluate if patients fulfill the recently developed “5-2-1” screening criteria for advanced Parkinson’s Disease (APD)[1] prior to treatment with levodopa-carbidopa intestinal gel (LCIG) and…Effect of an Increase in Dose of Istradefylline, an A2A Receptor Antagonist, in Levodopa (LD)-Treated Patients with Parkinson’s Disease (PD)
Objective: To observe whether increasing the istradefylline dose from 20 to 40mg/day provides more patients with meaningful clinical responses. Background: Istradefylline, a well-tolerated selective adenosine…GLYCOPAR – A randomized, placebo-controlled, 2-arm parallel-group superiority phase II study of glycopyrrolate for moderate-to-severe sialorrhea in Parkinson’s disease
Objective: To assess the 3-month efficacy and safety of glycopyrrolate for moderate-to-severe sialorrhea in Parkinson’s disease. Background: A systematic review reported that sialorrhea affects approximately…Spectrum of motor complications in advanced Parkinson’s disease: data from a large Romanian case series evaluated for suitability for device aided therapy
Objective: The objective was to describe the spectrum of motor complications in a large cohort of patients with advanced Parkinson’s Disease (APD) who received at…Study of prevalence of Axis-1 DSM-4 psychiatric disorders in patients with parkinsonism in a rural movement disorder clinic in Western India
Objective: To assess the prevalence of Axis-1 DSM-4 [The Diagnostic and Statistical Manual of Mental disorders] psychiatric disorders in patients with Parkinson’s disease [PD], atypical…Differential Gene Expression in Parkinson Disease and Chronic Traumatic Encephalopathy
Objective: The research would like to determine if similar overexpressed genes between CTE and PD may explain the occurrence of parkinsonism in CTE. This was…Gene panel testing in movement disorders: an efficient approach highlighting overlaps and heterogeneity
Objective: Our study aimed at developing a targeted sequencing approach using a customized panel of genes involved in movement disorders (MDs). Background: MDs are characterized…Determining Outcome of Deep Brain Stimulation Surgery in Parkinson’s Disease Patients
Objective: To assess the role of monogenic forms of PD and polygenic risk scores (PRS) on the motor and cognitive outcome of deep brain stimulation…
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