Functional connectome in Parkinson’s disease mild cognitive impairment
Objective: To unravel functional connectivity (FC) traits in Parkinson’s disease mild cognitive impairment (PD-MCI). Background: PD-MCI is a well-known risk factor for PD associated dementia.…Frequency-dependent abnormalities of intrinsic brain activity in Parkinson´s disease
Objective: The study objective was to assess the changes in amplitude of low frequency fluctuations (ALFF) in patients with Parkinson´s disease (PD) as compared to…Mitochondrial Complex 1, Sigma 1 Receptor and Synaptic Vesicle protein 2A density in early de novo patients with Parkinson’s Disease: pilot PET data
Objective: In this study, we evaluated the density of Mitochondrial complex 1 (MC1), sigma 1 receptor (s1R) and Synaptic Vesicle protein 2A (SV2A) in early…The role of Synaptic vesicle protein 2A (SV2A) in patients with Parkinson’s disease dementia and Dementia with Lewy bodies: An in vivo [11C]UCB-J PET study
Objective: We aimed to investigate the role of synaptic vesicle glycoprotein 2A (SV2A) in Parkinson’s disease dementia (PDD) and Dementia with Lewy bodies (DLB) using…Transcranial Photobiomodulation as an adjunct to Levodopa therapy in patients with Parkinson’s Disease; an open label pilot study
Objective: To explore the effects of transcranial Photobiomodulation (tPBM) on symptoms of Parkinson's Disease and establish this therapy's efficacy as an adjunct to Levodopa. Background:…Diagnosing Dementia with Lewy Bodies – Characterizing the prevalence and underlying relationships between core and supportive clinical features
Objective: To characterize the interrelationship between core and supportive features of Dementia with Lewy Bodies, and identify optimal methods for their detection to inform better…Utilization of Monotherapy and Combination Therapies in Advanced Parkinson Disease Patients During Levodopa-Carbidopa Intestinal Gel Treatment from the COSMOS Study
Objective: Assess the percentages of advanced Parkinson’s disease (APD) patients treated with levodopa-carbidopa intestinal gel (LCIG) as a monotherapy or with add-on PD medications and…Quantitative study of subthalamic ERG potassium channels in parkinsonian discharges
Objective: This study describes the role of the subthalamic ERG Potassium (ERG K+) ion channel conductance in cellular excitability in subthalamic nucleus (STN) neurons towards…Parkinson’s disease and intermittent hypoxia training: beneficial or harmful?
Objective: To systematically review the scientific evidence for beneficial or harmful effects of intermittent hypoxia that were used in Parkinson’s disease (PD) in clinical and…Effects of safinamide and rasagiline on in vivo glutamate release in 6-OHDA hemilesioned rats
Objective: To investigate the effects of safinamide (saf) and rasagiline on in vivo glutamate (Glu) release in the 6-hydroxydopamine (6-OHDA) hemilesioned rat model of Parkinson’s…
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