Modeling the Effect of Patient’s Perception of Non-Motor and Motor Function on Parkinson’s Disease Severity
Objective: To develop optimal models of patients' perception of non-motor and motor function on objectively measured Parkinson's disease (PD) severity. Background: There is increased interest…Tsallis entropy of EEG correlates with future cognitive decline in patients with Parkinson’s disease
Objective: To evaluate whether Tsallis entropy (TE) constitutes a possible functional characterization of neurodegeneration and a measure to predict progression of Parkinson’s disease (PD). Background:…How cognitive effort increases Parkinson’s tremor – an effictive connectivity fMRI study
Objective: To elucidate the neural mechanisms underlying tremor amplification during cognitive effort. Background: Parkinson’s tremor is related to cerebral activity in both basal ganglia and…Motor and non-motor symptoms differences between Vascular Parkinsonism (VP) and Parkinson’s Disease (PD) patients in early stages
Objective: Compare motor and non-motor symptoms between VP and PD patients. Background: VP is usually described as “lower-body parkinsonism”, with early gait difficulties and postural…Characterizing olfactory impairment in patients with Parkinson’s disease and related disorders
Objective: To characterize olfactory impairment in Parkinson’s disease (PD), multiple system atrophy (MSA) and progressive supranuclear palsy (PSP). Background: In the previous study, we found…Impaired fonction of mirror neurons and the role of levodopa in PD patients
Objective: Study of the emotional mirroring and its modulation by levodopa treatment in fluctuating PD patients with no significant cognitive burden as assessed by regular…The utility of DCTclock™ (the digital clock drawing test) for unmasking early cognitive decline in Parkinson’s disease
Objective: To examine the utility of DCTclock, for assessing subtle cognitive impairments in early Parkinson's disease (PD). Background: The identification of cognitive decline is crucial…Lymphocyte Senescence in Parkinson’s Disease
Objective: To characterise T- and B-lymphocyte senescence in early stage Parkinson’s disease (PD). Background: Evidence suggests that the immune system may contribute to PD aetiopathogenesis,…Hypermethylation of PGC-1α in peripheral blood leukocytes of patients with Parkinson’s disease
Objective: We aimed to explore the hypothesis that the PGC-1α variants are associated with its promoter methylations level thus affecting the PGC-1α mRNA expression. We…Movement disorders in chronic obstructive pulmonary disease (COPD); the effect of pulmonary disease to brain
Objective: To find out phenotypes of movement disorders related to COPD, and also associated factors. Background: Movement disorders in systemic diseases exactly are common in…
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