Preliminary evaluation of the Integrated Parkinson’s Care Network (IPCN): An integrated care model for complex needs
Objective: To conduct a preliminary evaluation of the IPCN for: 1) proof of concept, 2) processes refinement for its evaluation, and 3) assess the feasibility…A Novel Telerehabilitation Strategy to Prevent Falls in Parkinson’s Disease (PD)
Objective: To demonstrate that a novel physical therapy (PT) telerehabilitation program is feasible, reduces falls, increases balance confidence, & improves objective measures of gait/balance/postural stability…Objective assessment of Parkinson’s disease motor symptoms during leg agility test using motion sensors
Objective: To develop and evaluate machine learning methods for assessment of Parkinson’s disease (PD) motor symptoms using leg agility (LA) data collected with motion sensors…Neurocognitive outcomes of STN-DBS in patients with Parkinson’s disease: A 10-year review of local experiences in Hong Kong
Objective: The purpose of the study was to determine the long-term neurocognitive outcomes of STN-DBS for PD. Background: Cognitive disturbances is one of the most…The development of an instrument for measuring Parkinson’s patient empowerment
Objective: To develop a valid and reliable measurement scale of Parkinson’s patient empowerment index (PPEI). Background: Patient empowerment concept has been used as part of…Increased Parkin expression in a PARK20 (SYNJ1 mutation) iPSCs-based model
Objective: To generate mechanistic insight into how the SYNJ1 p.Arg258Gln mutation leads to neurodegeneration in juvenile Parkinsonism. Background: In humans, the SYNJ1 homozygous p.Arg258Gln missense…Genetic variations of SNCA and striatal dopaminergic dysfunction in patients with Parkinson’s disease
Objective: The aim of the present study was to investigate genetic variants in SNCA associated with accelerated deterioration in striatal dopaminergic activity. Background: Widespread a-synuclein…Molecular mechanisms of GCH1-associated Parkinson’s disease
Objective: To unravel the molecular mechanisms by which loss of GCH1 function enhances the risk of Parkinson´s disease (PD). Background: Loss-of-function mutations in GCH1 are…Contribution of individual motor signs to striatal dopamine deficiency in parkinsonism
Objective: The primary aim of the study was to investigate if any individual motor sign could be used clinically to predict striatal dopamine deficiency. Secondary…Characteristics of brain mri in patient with Parkinson’s disease
Objective: To investigate the characteristics and brain MRI findings in patient with Parkinson’s Disease Background: Parkinson's Disease is a chronic, progressive neurodegenerative disease that is…
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