The role of habenula and amygdala dysfunction in Parkinson’s disease patients with punding
Objective: To assess whether a functional dysregulation of the habenula and amygdala, as modulators of the reward brain circuit, contributes to Parkinson’s disease (PD)-punding. Background:…Beyond shuffling: Gait phenotypes in Parkinson’s Disease
Objective: To describe commonly observed gait phenotypes in a cohort of advanced Parkinson's Disease (PD) patients. Background: Gait disorders in PD are varied and complex. Even…Clinical Criteria for Subtyping Parkinson’s Disease: Differences in imaging and CSF biomarkers and longitudinal progression
Objective: To introduce a new practical classification method to assign individuals with Parkinson’s disease (PD) into distinct subtypes using baseline dataset, then to compare neuroimaging,…Effect of object size and obstacle avoidance on of Reach-to-Grasp Actions in Individuals with Parkinson’s disease
Objective: To investigate the effect of object size and obstacle on reach-to-grasp (RTG) actions in individuals Parkinson's disease (PD). Background: Previous studies reported impairments of…The impact of gastric acid suppressants and antacids on levodopa plasma concentration in patients with Parkinson’s disease
Objective: The levodopa tablet is prone to dissolve in acidic conditions. We investigated whether gastric acid suppressants (histamine-2 receptor antagonists or proton pump inhibitors) and…Deep brain stimulation in Parkinson’s disease: Outcome after more than nine years
Objective: The aim of this study is to examine the long-term effects of deep brain stimulation of the subthalamic nucleus (STN DBS) in Parkinson’s disease…Innovative recruitment strategies accelerate enrollment of genetic mutation carriers in the Parkinson’s Progression Markers Initiative (PPMI)
Objective: Determine feasibility of digital recruitment strategies, centralized screening, and a dedicated referral coordinator to enroll participants with LRRK2 or GBA mutations into PPMI, a…Efficacy and Safety of Therapeutic Interventions to Treat Motor Symptoms in Late Stage Parkinson’s Disease: A Systematic Review
Objective: Evaluate the efficacy and safety of therapeutic interventions to treat the motor symptoms in late stage PD. Background: PD patients in late stage are…Aberrant resting state functional brain networks in patients with Parkinson’s disease and visual hallucinations
Objective: To explore the neural correlates of Visual Hallucinations (VH) in patients with Parkinson’s disease (PD). Background: Psychosis is one of the commonly observed non-motor…Utility of DaTscan Imaging in Differentiating Drug Induced Parkinsonism from IPD and Other Forms of Parkinsonism
Objective: To determine clinical correlates which differentiate drug induced Parkinsonism (DIP) from IPD and other forms of Parkinsonism using DaT-SPECT imaging. Background: DaT-SPECT imaging is…
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