Sodium butyrate attenuates rotenone-induced neurodegeneration via enhancing autophagy and preventing α-synuclein aggregation
Objective: To investigate whether sodium butyrate (NaB) could enhance autophagy and thus exert a neuroprotective effect through the modulation of α-synuclein in animal models of…Lrrk2 alleles modify host response to microbial infections
Objective: The mechanisms by which allelic changes in LRRK2 modulate the susceptibility to Parkinson's disease, Crohn's disease and leprosy remain unknown. We hypothesized that leucine-rich…Analysis of LINGO1 and LINGO2 genes in essential tremor and Parkinson’s disease
Objective: We studied the involvement of LINGO1 and LINGO2 in Russian patients with ET and PD. Background: Genetics of ET is unclear. Three candidate loci…Resting-state functional connectivity of subthalamic nucleus in different phenotypes of Parkinson’s disease
Objective: To explore the different resting-state functional connectivity of subthalamic nucleus (STN) in different phenotypes of Parkinson's disease (PD). Background: The STN is one of…The relationship between cognitive task and postural stability in the early stages of Parkinson’s disease
Objective: To examine the presence of dual task interference with cognitive tasks on postural stability in the early stages of Parkinson's disease (PD). Background: There…Parkinson’s disease-linked mutation in DNAJC13 causes specific trafficking defect in endosomal pathway
Objective: The aim of this study is to investigate the effect of mutant DNAJC13 on the vesicle transport machinery using cultured cellular model. Background: Recently,…Combined effects of visual and auditory cues on gait initiation in Parkinson’s disease
Objective: To investigate the combined effects of visual and auditory cues on gait initiation and to investigate the correlation between the clinical rates of gait…Onset-related subtypes of Parkinson’s disease differ in the patterns of striatal functional connectivity: A resting-state functional MRI study
Objective: No. Background: Parkinson's disease is a surprising heterogeneous neurodegenerative disorder. Early onset Parkinson's disease (EOPD) and late onset Parkinson's disease (LOPD) were reported to…Effects of zonisamide on dementia with Lewy bodies (DLB): A post-hoc analysis of phase 2 study for parkinsonism in DLB patients
Objective: To clarify the effects of zonisamide (ZNS) on the core symptoms of dementia with Lewy bodies (DLB), we performed a post-hoc analysis using data…Speech prosody impairment predicts cognitive decline in Parkinson’s disease
Objective: We assessed whether baseline speech prosodic parameters, alone or in combination with other predominantly non-dopaminergic symptoms may predict global cognitive decline as measured by…
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