Rasagiline treatment for sleep disorders in Parkinson’s disease (RaSPar) – Double-blinded, randomized, placebo-controlled, placebo run-in-phase, polysomnography clinical trial
Objective: To study the effects of Rasagiline on sleep disturbances measured by polysomnographic (PSG) evaluation of sleep efficacy and secondary measures as other sleep variables,…Sensor-based motor state detection in Parkinson’s disease to approach personalized therapy delivery
Objective: As primary objective, we acquire a data pool of medically-treated PD patients with motor fluctuations to determine the sensitivity and specificity of algorithms capable…Strategies to improve drug development efficiency through regulatory interactions, minimizing the placebo effect and improving data integrity within a phase 3 study of tozadenant in Parkinson’s disease patients with motor fluctuations (TOZ-PD)
Objective: To identify and implement strategies to improve the efficiency of drug development in Phase 3 studies. Background: Conducting global clinical trials can be challenging,…“Two odd targets” strategy in deep brain stimulation for Parkinson’s disease with unilateral dystonia
Objective: To describe a patient underwent deep brain stimulation (DBS) with different target in left and right. Background: DBS is a therapeutic option for movement…Efficiency of intraoperative microelectrode recording in patients with deep brain stimulation of the subthalamic nucleus. Three-year comparative research
Objective: The aim of the study was to evaluate the effect of intraoperative microelectrode recording in patients with deep brain stimulation of the subthalamic nucleus…Comparison of effect of variable deep brain stimulation (DBS) frequencies on gait and balance in Parkinson’s disease (PD) patients with either bilateral GPi or STN stimulators employing wearable wireless sensors
Objective: To compare the effect of variable Deep brain Stimulation (DBS) frequencies on gait and balance in Parkinson's disease (PD) patients with either bilateral GPi…How do patients experience deep brain stimulation surgery: A prospective patient satisfaction survey
Objective: To evaluate experience of patients who undergo Deep Brain Stimulation (DBS) surgery for treatment of different movement disorders, using patient survey questionnaires. Background: DBS…Comparison of cognitive and neuropsychological manifestations in patients with progressive supranuclear palsy (Psp) and Parkinson’s disease
Objective: 1) To compare the cognitive and neuropsychological manifestations between the patients with PSP and PD. 2) To find out the severity of caregivers distress…Do subjective ratings of the Parkinson’s disease sleep scale-2 converge with results from polysomnography in early Parkinson’s disease? – A report from the DeNoPa cohort
Objective: To test whether subjective sleep perception is associated with objective sleep parameters by comparing video-polysomnographic (vPSG) data from Parkinson's disease (PD) patients with scorings…Clinical and MRI-characteristics of drug-induced parkinsonism in Uzbekistan
Objective: To establish clinical and MRI morphometric differences between Parkinson's disease (PD) and Drug-induced parkinsonism (DP). Background: DP – is the most known side effect…
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