Classification of Advanced Parkinson’s Disease in OBSERVE-PD Patients Based on the MANAGE-PD Screening Tool
Objective: This post-hoc analysis evaluated uncontrolled patients from OBSERVE-PD identified as advanced Parkinson’s disease (APD) based on domains evaluated in section 2 of the MANAGE-PD…Backward Fall Protection Garment for patients of PSP and other Parkinsonian Syndromes.
Objective: To create a sensor controlled wearable system with an inflatable collar that offers protection against head, spine and shoulder girdle injuries in case of…Post-Covid-19 Parkinson’s disease: a Brazilian case series.
Objective: To describe two patients with post-COVID-19 Parkinson’s disease (PD) and discuss their possible causes. Background: PD is a neurodegenerative disorder characterized by motor and…Whole-transcriptome analysis of monocyte-derived macrophages from patients with Parkinson’s disease associated with mutations in the GBA gene
Objective: To understand specific molecular features of Parkinson’s disease associated with mutations in the GBA gene (GBA-PD), we analyzed the gene expression profile of peripheral-blood…Impulse control disorders in idiopathic REM sleep behaviour disorder and drug-naive Parkinson’s disease
Objective: To compare the frequency of impulse control disorders and compulsive behaviours (ICBs) in patients with iRBD and drug-naive PD, and to identify risk factors…Childhood-Onset Hemidystonia: A Transportophaty related to SLC6A3 missense mutation
Objective: To present the case of a childhood-onset hemidystonia carrying a homozygous SLC6A3 missense mutation. Background: Dystonia is a movement disorder characterized by sustained or…Akinetic-rigid motor presentation among adult-onset HD participants in Enroll-HD
Objective: To characterize a variant of adult Huntington’s disease (HD) with akinetic-rigid syndrome (ARS) as initial motor manifestation Background: HD Cases have been reported with…Long-Term Safety and Efficacy of Apomorphine Sublingual Film for “OFF” Episodes in Parkinson’s Disease
Objective: Evaluate long-term safety (LTS), tolerability, and efficacy of apomorphine sublingual film (APL) for on-demand treatment of “OFF” episodes in patients with Parkinson’s disease (PD).…Impact on Dyskinesia in Advanced Parkinson’s Disease Patients Treated with LCIG: Analysis from the COSMOS Study
Objective: Analyze the impact of levodopa-carbidopa intestinal gel (LCIG) treatment on dyskinesia duration and severity in advanced Parkinson’s disease (APD) patients participating in the COSMOS…Quantitative susceptibility mapping and blood neurofilament light chain differentiate between parkinsonian disorders
Objective: We employed Quantitative susceptibility mapping (QSM) to assess iron deposition in a larger sample size and explore whether combining QSM and NfL can improve…
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