Mutations of the VPS13A gene in a patient with Early-Onset Parkinson’s Disease: A case report.
Objective: To describe the case of a patient with early-onset Parkinson's Disease (PD) with variants of the VPS13A gene. Background: The vacuolar protein sorting 13A…European-Derived Parkinson’s Disease Polygenic Risk Score Model Is Associated With PD Status, UPDRS Score But Not Age At Onset Or Cognitive Impairment In An Egyptian PD Dataset
Objective: To assess the predictive ability of European-derived PD PRS model of 90 risk SNPs identified from the largest PD GWAS[1]in Egyptians and study its…Genome-wide Association Analyses Reveal Susceptibility Variants Linked to Parkinson’s Disease in the South African Population Using Inferred Global and Local Ancestry
Objective: The study aimed to investigate genetic risk factors for Parkinson’s disease (PD) in an admixed South African cohort using GWAS and local ancestry (LA)-GWAS…A Pan-Indian Genome-Wide Association Study of Parkinson’s Disease
Objective: To conduct the first pan-Indian genomic survey of PD across18 centres in India which included 4806 cases and 6363 controls. Background: The genetic architecture…Motor Outcomes Following Subthalamic Nucleus or Globus Pallidus Interna Deep Brain Stimulation in Early-Onset Parkinson’s Disease
Objective: Comparative outcomes between deep brain stimulation (DBS) targets in Early-onset Parkinson’s Disease (EOPD) patients are lacking. This study leverages the University of Florida’s (UF)…Are There Differences in Non-Motor Outcomes of Parkinson’s Disease Treated with GPi vs. STN Deep Brain Stimulation?
Objective: To evaluate the short-term effects of deep brain stimulation (DBS) of the Globus Pallidus internus (GPi) versus the Subthalamic Nucleus (STN) on non-motor symptoms,…Tracking The Role Of The Subthalamo-Temporal Network In Speech: A Deep Brain Stimulation-Electroencephalography Study
Objective: To identify deep brain stimulation (DBS)-related disruption of the subthalamic nucleus (STN)–temporal network as a possible source of STN-DBS induced dysarthria. Background: STN-DBS often…Analgesic Effect of Cannabidiol and Tetrahydrocannabinol(THC) on Pain Sensitivity in Reserpine Model of Parkinson’s Disease
Objective: The objectives of the study were to determine the effect of THC and CBD on:1. Thermal nociceptive threshold in reserpine induced Parkinson’s disease2. Mechanical…A Resting-State fMRI Study of Regional Homogeneity about Pain in Parkinson’s Disease
Objective: The purpose of our study is to explore the differences in ReHo patterns under acute and chronic pain conditions in Parkinson's disease (PD) patients, aiming to provide…Effects of Physiotherapy on Mood Disorders in Patients with MSA, PSP, and PD
Objective: To investigate the impact of physiotherapy on mood disorders such as apathy, anxiety, and depression in patients with Parkinson’s disease (PD), multiple system atrophy…
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