The study of genetic factors in motor levodopa-induced complications development in Russian patients with Parkinson’s disease
Objective: This study is aimed to explore the relationship between the single nucleotide polymorphisms (SNPs) in dopamine metabolism genes and development of motor side effects…Objective and easily performed assessment of fine motor skills to support the differential diagnosis of Parkinson’s disease and other movement disorders with tremor
Objective: To assess the ability of a handheld device and its accompanying data analytics to distinguish between Parkinson’s disease (PD) and other tremor disorders. Background:…Regular Exercise Regimen Associated with Reduced Prevalence of Depression in Parkinson’s Disease
Objective: To evaluate the association between exercise and depression in people with Parkinson’s disease (PD). Background: Depression and other neuropsychiatric disturbances are prevalent non-motor features…Clinical, environmental, and Technology-based gait measures in PD patients from a rural area in southwestern Colombia: a case-control pilot study
Objective: Describe the clinical characteristics, environmental exposures, and technology-based gait assessment of a sample of Parkinson’s disease patients in a rural area in southwestern of…Structural connectivity affecting freezing of gait after globus pallidus internus deep brain stimulation in Parkinson’s disease
Objective: We aim to investigate how structural connectivity of the brain affects gait freezing after globus pallidus internus (GPi) deep brain stimulation (DBS). Background: Freezing…Facial emotion recognition in Parkinson’s disease: the role of executive and affective domains
Objective: We aimed to explore facial emotion recognition (FER) skills in individuals with Parkinson’s disease (PD) by using a dynamic presentation of emotions across different…Double trouble: Association of malignant melanoma with sporadic and genetic forms of Parkinson’s disease and asymptomatic carriers of related genes in the PPMI study.
Objective: The aim of the present study was to assess the prevalence of malignant melanoma (MM) in sporadic and genetic Parkinson’s disease (PD) patients and…The Genetic Landscape of Parkinson’s disease in populations of non-Caucasian ancestry.
Objective: We aimed to review existing literature on the genetic background of Parkinson’s disease (PD) populations of non-Caucasian or mixed ancestry. Background: There has been…In Silico Study Reveals Cocaine Exposure Modulates Dopamine Neuron Firing Patterns by Inhibiting Small Conductance Calcium Activated Potassium Current
Objective: The neurological reason behind the loss of dopamine neurons causing Parkinson’s disease (PD) is an unsolved mystery. Background: As PD is identified as a…Optimizing patient-centric clinical outcome assessments for use in Parkinson’s disease clinical trials: Critical Path for Parkinson’s multistakeholder initiative
Objective: To advance patient-centric endpoints for use in early-stage Parkinson’s disease (PD) clinical trials. Background: Limitations with currently available patient-centric clinical outcome assessments (COAs) has…
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