Functional circuit abnormalities in Levodopa-induced dyskinesia in Parkinson’s disease: A systematic review
Objective: Levodopa-induced dyskinesia (LID) in Parkinson’s disease (PD) are involuntary movements caused by long-term treatment with dopaminergic replacement therapy (levodopa). During the cause of PD,…Impact of endpoint selection on sample size calculations for disease-modifying clinical trials in Parkinson’s disease patients with GBA1 mutations
Objective: To assess clinical trial sample size estimations under variable simulated scenarios for Parkinson’s disease (PD) patients with mutations in the β-glucocerebrosidade gene (GBA1). Background:…The development of a multiplex allele specific PCR to improve the diagnostic yield of NGS in the GBA gene screening
Objective: Our aim is to offer a complete and reliable diagnostic service excluding false negative. Background: Heterozygous variants in the GBA gene are the most…Sensor-based digital measurement of gait and wrist pronation-supination in clinically-defined classes of Parkinson’s disease progression identified by unsupervised clustering
Objective: To determine how sensor-based measurement of motor performances relate to the heterogeneity of clinical progression in early Parkinson’s disease (PD). Background: Observed disease progression…Neuropalliative communication curriculum: A review of the literature and needs assessment
Objective: We aim to improve neuropalliative education in neurology trainees by creating a reproducible didactic curriculum targeting specific communication techniques using case-based sensitive scenarios commonly…Closed-loop gait improvement in Parkinson’s Disease
Objective: The aim of this study was to measure gait parameters of patients with Parkinson’s Disease (PD) in everyday life situations and improve hypokinetic gait…Risk and protective factors in Parkinson’s disease: a simultaneous and prospective study with linear and machine learning models
Objective: To identify which risk/protective factors influenced most incident Parkinson's disease (PD) risk in a population of almost 24,000 Italian citizens, using both classical statistical…Taking the driver’s seat on Parkinson’s care
Objective: To provide insight into the unique service and support offered by the multidisciplinary health team to address the challenges and dilemmas faced by people…Effect of intensive Game-based neurorehabilitation (GBNR) on gait, balance and quality of life (QOL) in Parkinson’s patients: A prospective randomized control study
Objective: To assess changes in the gait, balance and QOL in PD patients subjected to intensive GBNR in comparison with conventional Neurorehabilitation (NR) therapy using…Effect of Best Practice Advisory on the administration of contraindicated medications to hospitalized patients with Parkinson’s disease and related disorders
Objective: To determine if a best practice advisory (BPA) reduced the orders and administration of contraindicated dopamine blocking agents (DBA) to hospitalized patients with Parkinson’s…
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