Clinic versus home dose optimization of apomorphine sublingual film in Parkinson’s Disease: cross-study comparison of safety
Objective: To compare the safety profile of clinic versus home dose optimization of apomorphine sublingual film (SL-APO) in patients with Parkinson’s disease experiencing OFF episodes.…Psychosocial factors impacting participation in a time-intensive deep brain stimulation study of individuals with Parkinson’s disease and dystonia
Objective: To evaluate psychosocial factors impacting the number of hours of participation in the first five months of a time-intensive deep brain stimulation (DBS) study.…Building a consensus conceptual model of meaningful symptoms and impacts in early Parkinson’s disease
Objective: To develop a consensus based conceptual model of meaningful symptoms and impacts in early Parkinson’s disease (PD) through aligning of PD qualitative research carried…Operationalising goal setting as an outcome measure: Experience from the PRIME-UK randomised controlled trial
Objective: To select a suitable primary outcome for the evaluation of a multicomponent intervention for people with parkinsonism. Background: The multicomponent PRIME model of care,…Effects of GBA1 mutations and STN-DBS on response inhibition in Parkinson’s disease
Objective: To determine specific pattern of cognitive dysfunction in Parkinson’s disease (PD) patients who are glucocerebrosidase mutation carriers (PD-GBA1) compared with non-mutation carriers with and…Are GBA–Parkinson Disease patients’ good candidates for Deep Brain Stimulation? A Longitudinal Multicentric study on a Large Italian Cohort
Objective: To investigate the impact of GBA variants on the long-term outcome of deep brain stimulation (DBS) in a large cohort of Italian PD subjects…Istradefylline effect on Parkinson’s Disease Tremor, Motor symptoms and non-Motor symptoms.
Objective: Istradefylline is FDA approved for use in patients with PD treated with carbidopa-levodopa to reduce off time. GUH Movement Disorder Group has observed that…Gene-environment interactions for Parkinson’s disease
Objective: The aim of this study was to test for interactions between PD-related genetic and phenotypic traits in the 23andMe, Inc. research cohort. Background: Parkinson’s…Multiple N-of-1 trials to investigate hypoxia-based treatment in Parkinson’s disease: safety and short-term effects
Objective: In this study, we describe the safety and short-term effects of the first hypoxia-based treatment trial in Parkinson’s disease by deploying a personalized multiple…An IMU- based Objective Quantification Method for Bradykinesia Evaluation in Parkinson’s disease
Objective: Proposing an inertial measurement unit (IMU)-based objective quantification method for bradykinesia evaluation in Parkinson’s disease (PD) using MDS UPDRS III. Background: MDS-UPDRS III rating…
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