Design of the Remote Optimization Adjustment and Measurement for Deep Brain Stimulation (ROAM-DBS) Randomized Controlled Trial Using Decentralized Patient Monitoring
Objective: To describe the design of the ROAM-DBS trial which measures outcomes of remote programming using remote monitoring. Background: A third of Parkinson’s Disease (PD)…‘Top of the POPPS’ – how we set up an online support group for Partners of People with Parkinson’s.
Objective: To provide useful peer and professional support for partners of people with Parkinson's (PWP)To be able to offer that support in a Covid safe…A qualitative study exploring the treatment burden and capacity of people with Parkinson’s and their caregivers
Objective: To explore experiences of treatment burden and capacity in Parkinson’s and identify potentially modifiable factors that can improve this Background: Treatment burden, the workload…Lymphocyte count/neutrophil-to-lymphocyte ratio and mild cognitive impairment in Parkinson’s disease
Objective: The present study aimed to elucidate whether i) lymphocyte count and neutrophil-to-lymphocyte ratio (NLR) can discriminate Parkinson's disease (PD) patients from healthy controls (HC);…Developing zebrafish CRISPR/Cas9 knockout models of Parkinson’s Disease to identify novel therapeutic targets.
Objective: Human patients present punctual mutations and/or small deletions in genes that have been associated with Parkinson’s disease, namely, park1, park2, park6, park7, and park8.…Anthropometric Changes in Parkinson’s Disease: Canadian Longitudinal Study on Aging
Objective: To explore the predictive role of anthropometric changes and development of Parkinson’s Disease (PD). Background: There is a tendency to lose weight in PD,…Correlation between cognitive/emotional factors and postural control in patients with Parkinson’s disease
Objective: This study aims to find associations between executive function, anxiety, depression, and reactive and anticipatory postural control domains. Background: Cognition and emotional state are…Genetic correlation and potential causal relationship between inflammatory bowel disease and Parkinson’s disease
Objective: The present study investigates shared genetic etiology between inflammatory bowel disease (IBD) and Parkinson’s disease (PD) using correlation and causality-based approaches. Background: The role…Subgroup analyses by Unified Parkinson’s Disease Rating Scale Part III (UPDRS-III) of patients treated with levodopa inhalation powder 84mg or placebo to treat OFF symptoms in patients with Parkinson’s disease (PD)
Objective: An analysis of the proportion of patients who turned ON after levodopa inhalation powder (CVT-301) 84mg treatment vs placebo, compared across subgroups of patients…Clinical presentation of SNCA Duplication Parkinsonism in a Family Kindred
Objective: To report phenotype variability in a family with SNCA duplication associated Parkinsonism. Background: Pathogenic variants in SNCA, the gene coding for α-synuclein, cause familial…
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