A systematic review to compare the effect of bilateral deep brain stimulation (STN versus GPI) on gait and balance in Parkinson’s disease
Objective: To compare the effect of bilateral sub-thalamic nucleus (STN) deep brain stimulation (DBS) and Globus pallidus interna (GPI) DBS on gait and postural stability in Parkinson’s…Dopamine agonist utilization prior to the initiation of device aided therapy: data from 150 patients with advanced Parkinson’s disease treated with Levodopa Carbidopa Intestinal Gel
Objective: Objective: To evaluate the usage of dopamine agonists (DA) as part of the last conventional dopaminergic treatment in a large cohort of consecutive patients…Embodied language in Parkinson disease: the case of demonstrative
Objective: Action language is recognized as impaired in Parkinson's disease (PD), proposing a functional role for the motor system in understanding action words [1]. This…The benefit of exclusive nocturnal administration of a levodopa-carbidopa intestinal infusion for severe refractory sleep behavior disorder in Parkinson’s disease
Objective: Treatment by continuous diurnal intestinal infusion of levodopa is effective in improving sleep quality in Parkinson's disease (PD), but its use exclusively at night…Estimating the Meaningful Within-Patient Change Threshold for the MDS-UPDRS Part III
Objective: To estimate the meaningful within-patient worsening threshold (MWPWT) of the Movement Disorders Society–Unified Parkinson’s Disease Rating Scale (MDS-UPDRS Part III in early-stage Parkinson's disease…Childhood Trauma and Parkinson’s Disease: Associations of Adverse Childhood Experiences, Disease Severity and Quality of Life
Objective: Objective: The goal of this study was to survey individuals with PD to evaluate whether intensity of childhood trauma is associated with individual symptoms,…Outcome and mortality of hospital admission with COVID-19 in parkinsonian syndromes
Objective: To evaluate features associated with poor outcome and mortality of COVID-19 in people with Parkinson’s disease (PD) and atypical Parkinsonian syndromes (APS) in a…Robust methods for missing covariates in longitudinal studies with application to biomarker research in Parkinson’s disease dementia
Objective: We propose a nonparametric method for handling different types of missing covariates in longitudinal studies. We show that the proposed method outperforms multiple standard…Microglial activation facilitates alpha synuclein propagation and neurodegeneration in αSyn preformed fibrils (PFF)-injected PD mouse model
Objective: To evaluate whether microglial activation aggravates synucleinopathy progression in Parkinson's disease (PD) mouse model. Background: Alpha-synuclein (αSyn) accumulation underlay the main pathological process of…Machine learning supervised classification study for Parkinson`s disease progression through graph-based feature selection method
Objective: The model helps neuro physicians/ neurologists to improve the PD symptoms, or therapeutic-treatment planning-procedures. Background: Artificial intelligence-based machine learning (AI-ML) supervised classification systems have…
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