Dopamine Transporter Imaging as a Predictor of Functional Outcomes in Parkinson’s Disease
Objective: To evaluate the prognostic value of dopamine transporter (DAT) imaging in predicting future disability, as well as motor and non-motor burden, in Parkinson’s disease…Dual task elicited premotor and supplementary motor activity as sensitive markers of mild Parkinson’s disease: an fNIRS analysis
Objective: This study aimed to explore dual-task (DT)-related cortical hemodynamic response (CHR) differences across healthy older adults (HOA), mild Parkinson’s disease (PD), and moderate PD…A Multi-Transcriptional Risk Score Approach to Parkinson’s Disease Prediction
Objective: To improve the prediction of Parkinson’s disease (PD) by examining aggregate profiles of gene expression in the form of transcriptional risk scores (TRS). Background:…Disclosing CLIA certified genetic results within the LARGE-PD Cohort in Peru: Preliminary results of the PD GENEration study
Objective: To characterize the Peruvian Parkinson’s disease (PD) cohort within the Latin American Research Consortium on the GEnetics of Parkinson Disease (LARGE-PD) that received a…16-years of Evaluations for Prodromal Parkinson Features in an At-Risk Cohort with Gaucher Disease
Objective: To evaluate prodromal features of Parkinson disease in a cohort of "at-risk" Gaucher patients and GBA1 carriers . Background: Variants in GBA1 mutations are…VPS13C: a Modifier Gene causing Suboptimal Response to Levodopa in Early-Onset Parkinson’s Disease
Objective: To describe a retrospective clinical study of four cases carrying heterozygous pathogenic variants in the VPS13C gene with a clinical diagnosis of Early-Onset Parkinson’s…The Global Parkinson’s Genetics Program: Expanding the Diversity of Neurological Disorder Data: 2025 Update
Objective: To broaden the available data for Parkinson's Disease (PD) and related disorders by integrating genetic data from more than 115,000 participants worldwide through genotyping…CAP-003, a CNS-targeted IV-delivered AAV Gene Therapy Developed for Patients with Parkinson’s Disease associated with GBA1 Mutations
Objective: CAP-003 is a next-generation gene therapy candidate, comprising a novel brain-tropic capsid paired with hGBA1 cargo, that was developed for administration as a single…Electrophysiological Mapping in Asleep vs. Awake DBS
Objective: We report our experience using microelectrode recording (MER) in asleep vs. awake patients for DBS targeting Background: MER has played a crucial role in…Predictors of Clinical Benefit from Adaptive DBS Compared to Conventional DBS in Parkinson’s Disease
Objective: To identify patient characteristics predicting adaptive deep brain stimulation (aDBS) superiority over conventional DBS (cDBS) in Parkinson's disease (PD). Background: Adaptive DBS, modulated in…
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