MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Parkinson’s"

  • 2025 International Congress

    Exploring Clinical and Neurophysiologic Predictors of Adaptive Deep Brain Stimulation Response in Parkinson’s disease

    T. Herrington, M. Beudel, J. Ostrem, S. Little, A. Ramirez-Zamora, L. Almeida, A. Fasano, T. Hassell, K. Mitchell, E. Moro, M. Gostkowski, N. Sarangmat, L. Tonder, Y. Tan, R. Summers, S. Stanslaski, H. Bronte-Stewart (San Francisco, USA)

    Objective: To evaluate clinical and neurophysiologic characteristics that may predict a positive clinical response to adaptive deep brain stimulation (aDBS) in patients previously stable on…
  • 2025 International Congress

    GT-02287 in Parkinson’s Disease: Interim Data from a Phase 1b Study

    R. Pozzi, T. Ignoni, M. Bosetti, M. Desciscio, A. Evans, V. Fung, A. Lehn, V. Miller, M. Rentería, R. Schwartz, D. Thyagarajan, S. Tisch, J. Taylor, J. Hannestad (Lugano, Switzerland)

    Objective: To evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of the brain-penetrant glucocerebrosidase (GCase) modulator GT-02287 in people with Parkinson’s disease with and without a…
  • 2025 International Congress

    Evaluation of Local Field Potential-guided DBS-programming in a Parkinson’s disease outpatient clinic

    V. Zentsch, N. Warneke, I. Aymanns, D. Putzer, T. Huchtemann, T. Warnecke, I. Claus (Muenster, Germany)

    Objective: To evaluate potential use and applicability of local field potential-guided DBS-programming under real-life conditions in a Parkinson’s disease (PD) outpatient clinic. Background: Deep brain…
  • 2025 International Congress

    Effects of Dynamic Neuro-Cognitive Imagery on FOG in People with Parkinson’s Disease: a Randomized Clinical Trial

    P. Silva, K. Honda, L. Santos, J. Garcia, B. Silva, M. Piemonte (Sao Paulo, Brazil)

    Objective: To compare the effects of an experimental intervention (EI) based on DNI with a control intervention (CI) of equal volume and intensity, excluding MP…
  • 2025 International Congress

    Quercetin Reduces mtDNA Release in PRKN-Deficient and Oxidatively Stressed SH-SY5Y Cells

    G. Agyeah, J. Ghelfi, L. Gallucci, K. Wasner, P. Antony, A. Rakovic, S. Pereira, A. Grünewald (Belval Esch-sur-Alzette, Luxembourg)

    Objective: This study investigates the role of Parkin deficiency in mitochondrial dysfunction and its contribution to mitochondrial DNA (mtDNA) release in Parkinson’s disease (PD). We…
  • 2025 International Congress

    Clinical Progression and Genetic Pathways in Body-First and Brain-First Par-kinson’s Disease

    M. Passaretti, D. Veréb, M. Mijalkov, Y. Chang, H. Zhao, J. Sun, B. Zufiria Gerbolés, G. Volpe, N. Rivera, M. Bologna, J B. Pereira (Stockholm, Sweden)

    Objective: We aim to assess Parkinson's disease (PD) phenotypes across both prodromal and clinical PD stages, track their pathological progression in vivo and identify potential underlying…
  • 2025 International Congress

    The Effectiveness of Rivastigmine in Parkinson’s Disease: Impact on Motor Symptoms, Gait, Cognitive Function, and Falls – A Systematic Review and Meta-Analysis of Double-Blind, Placebo-Controlled RCTs

    V. Byroju, J. Pitton Rissardo, A. Fornari Caprara (Camden, USA)

    Objective: To evaluate the efficacy of rivastigmine in patients with Parkinson’s disease (PD) by assessing its impact on motor symptoms, cognitive function, gait, falls, and…
  • 2025 International Congress

    Design of ORCHESTRA Study: Practical Experiences With Foslevodopa/Foscarbidopa Treatment in Advanced Parkinson’s Disease

    A. Johansson, E. Pekkonen, L. Dorresteijn, P. Schwingenschuh, J. Szász, L. Bergmann, M. O'Meara, J. Parra, M. Südmeyer (Helsinki, Finland)

    Objective: To describe the practical management of foslevodopa/foscarbidopa (LDp/CDp) for treating advanced Parkinson’s disease (aPD) in routine clinical practice using data collected through a patient…
  • 2025 International Congress

    Timing And Type Of Adverse Events Following Long-Term Treatment With Levodopa–Entacapone–Carbidopa Intestinal Gel (LECIG) Infusion – Data From The ELEGANCE Interim Analysis

    N. Smith, B. Amlani (Reading, United Kingdom)

    Objective: To evaluate the type and timing of occurrence of treatment-emergent adverse events (AEs) in people with advanced Parkinson’s disease (PD) following up to one…
  • 2025 International Congress

    Transcranial Direct Current Stimulation (tDCS) to Enhance Cognitive Function in Parkinson’s Disease: A Systematic Review and Meta-analysis with Implications for African Healthcare

    O. Uwishema (Kigali, Rwanda)

    Objective: This study assesses the efficacy of transcranial direct current stimulation (tDCS) in improving cognitive function in Parkinson’s disease (PD) patients and explores its relevance…
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