Efficacy and Safety of IPX203 and Levodopa-Carbidopa Intestinal Gel (LCIG) Compared to Immediate-Release Carbidopa-Levodopa in Parkinson’s Disease: A Systematic Review and Meta-Analysis
Objective: To conduct the efficacy and safety of IPX203, an extended-release carbidopa-levodopa formulation, and LCIG, a continuous levodopa infusion, compared to Immediate-Release Carbidopa-Levodopa (IR CD-LD)…Solengepras: An Investigational Therapy with Potential Benefits on Functional and Non-Motor Measures in Parkinson’s Disease (PD)
Objective: Solengepras is a GPR6-inhibitor that is being studied as an investigational treatment for Parkinson’s Disease (PD). Background: GPR6 is a novel G-protein-coupled receptor found…Advancements in Microbiome Research: Total Microbial Load, Differential Absolute Abundance, and Correlations with Immune Transcriptomics
Objective: Quantify total microbial load in the gut microbiome of people with Parkinson’s disease (PD) and compare the absolute abundance of bacterial taxa between PD…A novel virtual home-safety fall prevention program for Parkinson’s Disease
Objective: To determine the feasibility and preliminary efficacy of a novel virtually-delivered protocol targeting extrinsic environmental fall risk factors in the homes of persons with…Istradefylline for Freezing of Gait in Parkinson’s Disease: A Systematic Review and Meta-Analysis
Objective: To evaluate the effects of istradefylline on motor function and freezing of gait (FOG) in patients with Parkinson’s disease (PD). Background: FOG is a…Risk factors for central nervous system side effects of amantadine
Objective: The purpose of this study was to investigate the threshold blood level of amantadine and risk factors for central nervous system (CNS) side effects…Influence of age at onset on medication profile in patients with Parkinson’s disease: A prospective study from a tertiary care center in India
Objective: To study the effect of age at onset on the medication profile of various Parkinson's disease (PD) related medications. Background: Multiple factors determine the…Therapeutic Effect and Mechanism of Targeted Nano-selenium in Mouse Model of Parkinson’s Disease Induced by MPTP
Objective: In the present study, we developed a nanozyme (Se@PB-ACPP) incorporating selenium-loaded Prussian blue (PB) and modified it with an activatable cell-penetrating peptide (ACPP) to…Monitoring Parkinson’s Disease in the Dental Chair
Objective: Our goal is to bridge the mechanistic knowledge gap on the Microbiota-Gut-Oral-Brain-Axis (MGOBA)’s role in Parkinson’s disease (PD) pathogenesis through a case-control, proof-of-concept, observational…iPad App-based Eye Tracking for the Early Detection of Parkinson’s Disease
Objective: Demonstrate the concurrent validity, diagnostic accuracy, and early detection ability of an iPad app-based eye tracking tool for the early detection of Parkinson’s disease…
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