Artificial Intelligence and Visual Analysis of Movements in Parkinson’s Disease
Objective: To evaluate the use of artificial intelligence in the analysis and classification of movements in Parkinson's disease. Background: Artificial intelligence (AI) is a powerful…Acceptability and user experience of the electronic versions of the MDS-UPDRS and MDS-NMS scales
Objective: This study aims to evaluate the user experience of the newly developed electronic versions of the MDS Unified Parkinson's Disease Rating Scale (e-MDS-UPDRS) and…Identification of Fall Risk in Patients with Parkinson’s Disease Through Telemonitoring
Objective: This work presents an analysis of real-world, device-reported outcomes from patients with Parkinson’s disease (PD) in Greece. A total of 82 patients were included…Handwriting Features in Patients with Isolated REM Sleep Behaviour Disorder
Objective: To assess iRBD patients’ handwriting features and develop a rating scale capable of detecting early hallmarks of disease. Background: Handwriting changes, such as micrographia,…Slc2a13, a risk gene for Parkinson’s disease associated with Snca and Lrrk2
Objective: To exploit the potential function of the risk gene Slc2a13 in PD progression. Background: 越来越多的证据证实了总体遗传位点和候选基因对帕金森病的贡献，以及两个最确定的风险基因，即α-突触核蛋白（Snca）和富含亮氨酸的重复激酶2（Lrrk2）。Slc2a13 编码哺乳动物肌醇转运蛋白，被认为是一种群体依赖性风险基因。越来越多的证据支持这样一种观点，即 Slc2a13 活性的改变强调了 PD 的发展。剖析转运蛋白活性降低如何导致多巴胺能神经元变性和丧失，可能会进一步加深我们对功能的理解。 Method: A total of 338 cases…Distinct patterns of Gene Expression in Skin-biopsy Derived Fibroblasts of Patients with Parkinson’s disease
Objective: In this study, we aimed to investigate global gene expression alterations in cultured skin fibroblasts from individuals with idiopathic Parkinson’s disease (PD) compared to…Comorbidities in genetic Parkinson’s Disease: comparison between LRRK2, GBA1, and non-mutated PD
Objective: To examine the occurrence of medical comorbidities associated with genetic form of Parkinson’s disease (GBA1-PD and LRRK2-PD) compared to a cohort of non-mutated PD…Expanding Diversity of Parkinson’s Disease and Related Disorders Genetic Data: from the Global Parkinson’s Genetics Program
Objective: To expand the research dataset for Parkinson’s Disease (PD) and related disorders by including >50,000 participants globally who have been genotyped or whole genome…LRRK2 Gene Mutation in Parkinson’s Disease
Objective: We aim to describe the clinical characteristics of PD linked to an LRRK2 mutation. Background: One of the most common monogenic forms of Parkinson's…Correlation of Neural Sensing with the Volume of Neural Activation within the Desired Patient-Specific Anatomical Target in Deep Brain Stimulation for Parkinson’s Disease
Objective: Investigate the correlation between power in local field potential (LFP) beta band sensed from the subthalamic nucleus (STN) and the volume of neural activation…
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