MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Presynaptic dopaminergic system"

  • 2025 International Congress

    Staging Disease Progression from Prodromal to Overt Stage of Alpha-synucleinopathies

    D. Arnaldi, M. Roascio, E. Antelmi, F. Biscarini, L. Baldelli, V. Brunetti, E. Capriglia, E. Casaglia, A. Castelnuovo, G. Della Marca, L. Ferini-Strambi, R. Ferri, M. Figorilli, A. Galbiati, B. Guarnieri, D. Hoxhaj, F. Di Laudo, C. Liguori, S. Marelli, P. Mattioli, M. Mulas, B. Orso, M. Pardini, F. Pizza, F. Placidi, G. Plazzi, F. Provini, L. Sambati, M. Puligheddu, G. Arnulfo (Genova, Italy)

    Objective: To compute a disease progression model of the prodromal to overt synucleinopathy continuum, usable at single subject level. Background: Progression milestones to stage patients…
  • 2025 International Congress

    Hippocampal-striatal interaction and cognitive decline in Parkinson’s disease with mild cognitive impairment

    S. Tan, X. Zhang, J. Wen, X. Xu, Z. Zhang, J. Xu (Hangzhou, China)

    Objective: We aimed to investigate the interaction between hippocampus and dopaminergic pathways in PD with mild cognitive impairment (PD-MCI). Background: Dysfunction of striatal dopaminergic neurotransmitter…
  • 2025 International Congress

    Exploring the Association between Autonomic Responses and Dopaminergic Pathways in Early Parkinson’s Disease

    E. Garasto, A. Stefani, M. Pierantozzi, N. Mercuri, A. Chiaravalloti, C. Rocchi (Rome, Italy)

    Objective: To assess if cardiovascular dysautonomia, evaluated by autonomic function tests (AFTs), is related to dopaminergic nicgrostriatal loss and other non-motor symptoms in early Parkinson…
  • 2024 International Congress

    Value of DaTSPECT in rare movement disorders: neurodegenerative diseases

    E. Ardila Jurado, L. Zünd-Hofer, F. Brugger, G. Kägi (St Gallen, Switzerland)

    Objective: To explore the expanding indications of dopamine transporter imaging (DaT Spect) beyond the established indications. Background: DaTSPECT is a well-established method to rule out…
  • 2024 International Congress

    Associations Between Striatal Dopamine Transporter Binding and Motor Asymmetry In De Novo PD with and Without RBD

    H. Hameed, S. Elasfar, K. Ehgoetz Martens (Waterloo, Canada)

    Objective: To evaluate the associations between striatal and motor asymmetry in Parkinson’s disease with probable RBD compared to without. Background: Parkinson’s disease is typically characterized…
  • 2024 International Congress

    The value of DaT SPECT in rare movement disorders: acquired diseases

    E. Ardila Jurado, L. Zünd-Hofer, F. Brugger, G. Kägi (St. Gallen, Switzerland)

    Objective: To explore the expanding indications of dopamine transporter imaging (DaT SPECT) beyond the already known indication in Parkinson Diseases (PD) Background: DaT SPECT is…
  • 2023 International Congress

    A 20-Year Follow-Up Case Report with Three DaT-SPECT Scans in Parkinson’s Disease Diagnosis

    S. Virameteekul, K. Bhatia (London, United Kingdom)

    Objective: To describe a patient who underwent multiple DAT-SPECT scans over a 20-year clinical follow-up period in three distinct clinical settings: a normal scan excluding…
  • 2023 International Congress

    Functional Neuroimaging and Follow up trends in Drug induced movement disorders.

    V. Mathur, A. Shetty, H. Shah, V. Lele, P. Wadia (Jaipur, India)

    Objective: To analyse the role of presynaptic dopaminergic imaging (TRODAT/ F Dopa PET) scans to predict long-term outcomes in patients of new onset parkinsonian symptoms…
  • 2022 International Congress

    Presynaptic dopamine compartmentalization defects initiate auxilin-mediated parkinsonism

    D J. Vidyadhara, M. Somayaji, N. Wade, H. Zhao, S. Narayanan, J. Gupta, T. Lam, D. Sames, L. Greene, D. Sulzer, S. Chandra (New Haven, USA)

    Objective: To evaluate the pathogenic mechanisms for auxilin-mediated Parkinson’s disease (PD). Background: Auxilin participates in uncoating of clathrin-coated vesicles (CCVs), thereby facilitating synaptic vesicle (SV)…
  • 2022 International Congress

    Longitudinal combined 11C UCB J and 18F FE PE2I PET imaging of presynaptic terminal loss in early Parkinson’s disease.

    A. Delva, K. van Laere, W. Vandenberghe (Leuven, Belgium)

    Objective: To longitudinally assess presynaptic terminal loss in vivo over a 2-year period in people with early Parkinson’s disease (PD). Background: Imaging tools that allow…
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