DCN-PPN Pathway Activation Improves Motor Dysfunction via Synaptic Plasticity in Parkinson’s Disease
Objective: To define the anatomical and functional connectivity of the DCN-PPN pathway, determine its alterations in PD, and investigate whether impaired synaptic plasticity in this…Adult Onset Isolated Lower Limb Dystonia: Clinical Phenomenology and Dopaminergic Imaging Correlates
Objective: To characterise adult-onset isolated unilateral LLD and examine the relationship between clinical findings and presynaptic dopaminergic imaging. Background: Adult-onset lower limb dystonia (LLD) may raise suspicion…Visualization of Small Brainstem Nuclei With the Ultra-High Performance NeuroEXPLORER PET Camera: a Comparison Study Using 18F-AV133
Objective: To compare the performance of 18F-AV133 between NeuroEXPLORER (NX) and standard resolution Siemens Biography (mCT) positron emission tomography (PET) cameras in people with Parkinson's…Staging Disease Progression from Prodromal to Overt Stage of Alpha-synucleinopathies
Objective: To compute a disease progression model of the prodromal to overt synucleinopathy continuum, usable at single subject level. Background: Progression milestones to stage patients…Hippocampal-striatal interaction and cognitive decline in Parkinson’s disease with mild cognitive impairment
Objective: We aimed to investigate the interaction between hippocampus and dopaminergic pathways in PD with mild cognitive impairment (PD-MCI). Background: Dysfunction of striatal dopaminergic neurotransmitter…Exploring the Association between Autonomic Responses and Dopaminergic Pathways in Early Parkinson’s Disease
Objective: To assess if cardiovascular dysautonomia, evaluated by autonomic function tests (AFTs), is related to dopaminergic nicgrostriatal loss and other non-motor symptoms in early Parkinson…The value of DaT SPECT in rare movement disorders: acquired diseases
Objective: To explore the expanding indications of dopamine transporter imaging (DaT SPECT) beyond the already known indication in Parkinson Diseases (PD) Background: DaT SPECT is…Value of DaTSPECT in rare movement disorders: neurodegenerative diseases
Objective: To explore the expanding indications of dopamine transporter imaging (DaT Spect) beyond the established indications. Background: DaTSPECT is a well-established method to rule out…Associations Between Striatal Dopamine Transporter Binding and Motor Asymmetry In De Novo PD with and Without RBD
Objective: To evaluate the associations between striatal and motor asymmetry in Parkinson’s disease with probable RBD compared to without. Background: Parkinson’s disease is typically characterized…A 20-Year Follow-Up Case Report with Three DaT-SPECT Scans in Parkinson’s Disease Diagnosis
Objective: To describe a patient who underwent multiple DAT-SPECT scans over a 20-year clinical follow-up period in three distinct clinical settings: a normal scan excluding…
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