A trail towards understanding cognitive impairment in PSP
Objective: To investigate cognitive impairment in 22 patients with Progressive Supranuclear Palsy with Richardson syndrome (PSP-RS). Background: PSP is a neurodegenerative disease and common differential…APOE effect on Progressive Supranuclear Palsy phenotypes
Objective: To assess the influence of the Apolipoprotein E (APOE) gene variants on Progressive supranuclear palsy (PSP) phenotypic expression. Background: PSP is a rare neurodegenerative…Imaging Tau in Atypical Parkinsonisms: Meta-Analysis of in vivo PET Imaging Findings
Objective: To determine the most accurate and reliable tau PET tracers for providing differential diagnosis of PSP and CBD from PD. Background: Parkinsonism is classified…The Magnetic Resonance Parkinsonism Index as a diagnostic marker for differentiating PSP from IPD
Objective: The Magnetic Resonance Parkinsonism Index (MRPI) has been proposed as an enhancement of the Midbrain to Pons Ratio (MTPR) as a diagnostic tool for…COMBINED CSF α-SYN RT-QuIC, CSF NFL AND MIDBRAIN-PONS PLANIMETRY IN DEGENERATIVE PARKINSONISMS: FROM BEDSIDE TO BENCH, AND BACK AGAIN
Objective: (1) to assess the combined diagnostic ability of CSF NFL, CSF RT-QuIC α-SYN and midbrain/pons MRI measures in degenerative parkinsonisms; (2) to interpret results…Cognitive and Psychiatric Correlates of Fear of Falling in Progressive Supranuclear Palsy and Multiple System Atrophy
Objective: To evaluate the clinical correlates of fear of falling (FoF) in patients with Progressive Supranuclear Palsy (PSP) and Multiple System Atrophy (MSA) Background: FoF…Probable Four-repeat tauopathy criteria in Corticobasal Syndrome: diagnostic accuracy, clinical features and imaging biomarkers
Objective: To compare the “probable four-repeat (4R)-tauopathy” criteria[1] with the clinical research(cr) criteria for corticobasal degeneration (CBD) [2] regarding diagnostic accuracy to predict a negative…Effects of venlafaxine on neuropsychiatric and motor symptoms in patients with progressive supranuclear palsy
Objective: This prospective, ongoing, interventional trial is related to the ProPSP registry and aims to characterize the effects of venlafaxine, a serotonin-norepinephrine reuptake inhibitor, on…Variability in Age of Onset, Age of Diagnosis and Age of Death for Progressive Supranuclear Palsy Patients Among Three Racial Groups in Hawai`i
Objective: To examine if differences in age of symptom onset, age of diagnosis, age of death, and number of years lived after diagnosis exist for…Explorative study of analysis of the role of NFL and IGF1 in Indian patients with PSP and its clinical correlation.
Objective: In this prospective cross sectional case control study, we have investigated the relationship of serum levels of Neurofilament light chain and Insulin like growth…
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