Insular dopamine deficits in prodromal α-synucleinopathies
Objective: aim of the study was to evaluate the dopamine binding characterizing subjects both at prodromal and symptomatic stages in α-synucleinopathies, by means of ROI-based…Multimodal MRI assessment of the substantia nigra in premotor and motor stages of parkinsonism
Objective: To investigate substantia nigra (SN) MRI abnormalities through Neuromelanin (NM) and diffusion MRI (dMRI) with Neurite Orientation Dispersion and Density Index (NODDI) in the…Screening of REM Sleep Behavior Disorder and the relation with parkinsonism symptoms in the elderly in southern Brazil: a preliminary population-based study
Objective: To describe the preliminary screening profile for suspected REM sleep behavior disorders (RBD) and association with parkinsonian symptoms in the elderly in a population-based…Autonomic Nervous System Dysfunction in idiopathic REM sleep behaviour disorder
Objective: To characterise autonomic impairment in REM sleep behaviour disorders, and to investigate the pathophysiological link between autonomic impairment and REM sleep behaviour disorder Background:…Striatal Subregion Analysis Associated with REM Sleep Behavior Disorder in Parkinson’s disease
Objective: Herein we evaluated the regional selectivity of presynaptic striatal dopaminergic denervation associated with RBD in drug-naive early PD. Background: REM sleep behavior disorder (RBD)…Marker Progression and Sample Sizes Estimates for Trials in Prodromal Parkinson’s Disease: A Multicenter Study
Objective: To inform the design of randomized neuroprotective trials in prodromal Parkinson’s disease (PD) by assessing the progression of prodromal markers in idiopathic rapid eye…Evaluation of rapid eye movement behavioral disorder (RBD) in sporadic adult onset ataxia (SAOA)- A prospective observational study
Objective: 1. To evaluate the presence of RBD in patients with SAOA2. To follow up patients of SAOA with RBD whether they develop multiple system…Gray matter volume of proposed brain-first and body-first Parkinson’s disease subtypes
Objective: The aim of this study was to test if markers of the brain-first Parkinson’s disease (PD) subtype are associated with a greater or more…Preliminary results on the cognitive profile in prodromal Parkinson’s disease – a prospective study
Objective: This study aims to investigate the cognitive profile in people with REM-sleep behavior disorder (RBD) and hyposmia, in a prodromal Parkinson’s disease (PD) cohort.…The benefit of exclusive nocturnal administration of a levodopa-carbidopa intestinal infusion for severe refractory sleep behavior disorder in Parkinson’s disease
Objective: Treatment by continuous diurnal intestinal infusion of levodopa is effective in improving sleep quality in Parkinson's disease (PD), but its use exclusively at night…
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