Development and validation of clinical scales for defining RBD severity in participants of the North American Prodromal Synucleinopathy (NAPS) consortium
Objective: The objective of this study is to assess the internal validity of the REM Sleep Behavior Disorder (RBD) symptom severity scale (RBDSSS) and its…Long-term Deutetrabenazine Safety on Motor, Psychiatric, and Cognitive Measures in Individuals With Chorea Associated With Huntington Disease
Objective: To evaluate long-term deutetrabenazine safety on motor, psychiatric, and cognitive measures in participants with chorea associated with Huntington disease (HD). Background: Deutetrabenazine, a vesicular…Developmental Validity of the revised improved version of the Fragile X-associated Tremor Ataxia Syndrome Rating Scale (FXTAS-RS)
Objective: To qualitatively validate the revised improved version of the Fragile X-associated Tremor Ataxia Syndrome Rating Scale (FXTAS-RS) for motor signs assessment. Background: Clinimetric analyses…Impact of the delayed diagnosis in the prognosis of Parkinson’s disease.
Objective: To evaluate the difference of motor and non-motor dysfunction, and quality of life in Parkinson’s disease (PD) patients with and without delayed diagnosis. Background:…The Comparison of Constipation scoring system scales between Parkinson’s disease and non-Parkinson’s disease patients with constipation
Objective: This study aims to identify differences of constipation symptoms in detail by using the constipation scoring system between PD patients and non-PD patients. Background:…Exploratory delayed-start analysis of PASADENA evaluating the efficacy of prasinezumab on motor progression and motor complications in early-stage Parkinson’s disease
Objective: To evaluate the effect of prasinezumab on motor progression and motor complications in early-stage Parkinson’s disease (PD) using an exploratory delayed-start analysis of Part…Impact of SARS-CoV-2 vaccine in Parkinson’s disease
Objective: To evaluate the impact of SARS-CoV-2 vaccine on motor and non-motor symptoms in Mexican people with Parkinson's disease (PwP). Background: Nowadays, as a consequence…Validation of a patient-reported functional mobility composite score (FMCS) in people with typical Parkinson’s disease
Objective: To investigate the convergent and discriminative validity of a patient-reported FMCS in people with typical PD (PwP). Background: Although a patient-reported instrument is less…Estimating the Meaningful Within-Patient Change Threshold for the MDS-UPDRS Part III
Objective: To estimate the meaningful within-patient worsening threshold (MWPWT) of the Movement Disorders Society–Unified Parkinson’s Disease Rating Scale (MDS-UPDRS Part III in early-stage Parkinson's disease…Cerebellar and other motor symptoms in Huntington’s Disease: A multiple scale correlation study
Objective: To describe the cerebellar symptoms and other accompanying movement disorders in Huntington's Disease (HD). Background: HD is a pathological entity whose etiological substrate is…
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