Brain SPECT in Patients with Akinetic-Rigid Syndrome Secondary to Radiotherapy
Objective: The aim of this study is to evaluate the results of brain single photon emission computed tomography (SPECT) with 123-iodine ioflupane in patients with brain…Disease stage and nigrostriatal integrity predict motor progression in individuals with early Parkinson’s disease
Objective: To identify predictors of motor progression in individuals with early Parkinson’s disease (PD), who are either untreated or treated with monoamine oxidase B (MAO-B)…Reversible MIBG Abnormalities in Subjects at Risk for Synucleinopathy: 12 months data
Objective: To investigate the long-term effects of the adrenergic blocker carvedilol on I-MIBG myocardial uptake in subjects with REM sleep behavior disorder (RBD) and other…Serial DaT-SPECT imaging in asymptomatic carriers of LRRK2 G2019S mutation: 8-years follow-up
Objective: To characterize the 8-year progression of clinical and imaging biomarkers in a cohort of asymptomatic LRRK2 G2019S carriers and to assess its utility as predictors of…A direct longitudinal comparison of free water diffusion MRI and DaTscan SPECT in Parkinson’s Disease.
Objective: To compare the within-subject longitudinal sensitivity of PD biomarkers derived from DaTscan and Diffusion MRI. Background: Parkinson’s Disease (PD) is associated with impaired striatal…Aberrant dopamine transporter and functional connectivity patterns in LRRK2 and GBA non-manifesting carriers
Objective: We aimed to study the association between presynaptic striatal dopamine uptake and functional connectivity (FC) patterns among healthy first-degree relatives of PD patients with…DAT-IQ improves power to detect longitudinal change in DaT deficit in SURE-PD3
Objective: DATIQ has been developed as a novel analytical approach to improve the sensitivity and statistical efficiency of dopamine transporter (DaT) SPECT quantification over previously…Substantianigral involvement on Tc99mDaTSPECT-a novel and under recognised imaging finding in Parkinsonian Disorders
Objective: To assess feasibility of identifying SN involvement on DaTi, correlate with laterality of motor symptoms and compare with loss of nigrosome-1 hyperintensity on SWI . Background:…Comparison of 123I-MIBG myocardial scintigraphy and 123I-FP-CIT SPECT between dementia with Lewy bodies and Parkinson’s disease
Objective: The objective of this study was to compare the nuclear medicine images of dementia with Lewy bodies (DLB) and Parkinson's disease (PD) patients and to extract findings…Quantification of 123I-ioflupane Striatal Uptake and Individual Patient Diagnostic Predictions: Degenerative Parkinson’s disease, Non-Degenerative Parkinsonism and Tremor Disorders
Objective: To develop a fully automated quantitative method to analyse routinely acquired 123I-ioflupane (DaTSCAN) data to aid diagnostic predictions in patients with Parkinson’s disease, non-degenerative…
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