Evolution of mild Parkinsonian signs in a longitudinal population-based cohort
Objective: To investigate evolution of mild Parkinsonian signs (MPS) in an ongoing longitudinal study on Parkinson's disease (PD). Background: Mild motor impairmant may progress to…MRI signatures of the brain of Parkinson’s disease and idiopathic REM sleep behavioral disorder subjects
Objective: To characterize brain microstructural integrity, iron loads, and functional connectivity in 10 idiopathic rapid eye movement sleep behavior disorder (RBD), 10 Parkinson's disease (PD)…Application of the MDS research criteria for prodromal Parkinson’s disease to the longitudinal population-based Bruneck study cohort
Objective: To quantify the prevalence of prodromal phase of Parkinson's disease (PD) defined per 2015 MDS research criteria and their potential to predict incident clinically…Targeted over-expression with AAV-mediated human α-synuclein in a rat model of Parkinson’s disease – Validation of novel fine motor functional effects
Objective: Targeted over-expression of human α-synuclein using viral-vector mediated gene delivery into the substantia nigra of rats and non-human primates has been reported to lead…Jan Evangelista Purkinje: Contributions to study of anatomy and physiology of movement disorders
Objective: The objective is to retrieve historical articles highlighting Purkinje's research contributions. Background: Purkinje made seminal contributions to our understanding of anatomy and physiology especially…Detecting brainstem changes in Parkinson’s disease using quantitative MRI
Objective: 1. Can brainstem changes be detected using quantitative MRI (qMRI). 2. How many subjects would be required to detecting changes in brainstem regions affected…
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